Follicular dendritic cell sarcoma: A diagnostic challenge !

被引：9

作者：

Malik, Ajay ^{[1
]}

Veniyoor, Ajit

Fanthome, Barnard

Dutta, Vibha ^{[1
]}

机构：

[1] AFMC, Dept Pathol, Pune, Maharashtra, India

来源：

JOURNAL OF CANCER RESEARCH AND THERAPEUTICS | 2012年 / 8卷 / 02期

关键词：

Anal canal; Follicular dendritic cell sarcoma; immunohistochemistry; FEATURES; MARKER;

D O I：

10.4103/0973-1482.98998

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Follicular dendritic cell sarcoma (FDCS) is a spindle cell neoplasm of histiocytic-dendritic cells origin. It is known to occur in lymph nodes and rarely has been reported in extranodal tissues like head and neck, mediastinum and gastrointestinal tract. We herein report the first FDCS arising from anal canal in a 56-year-old man. The tumor was composed of bland short spindle cells in focal whorl formation with interspersed few lymphocytes. The tumor cells were classically positive for CD21, CD23, CD35 and vimentin. Despite its misleading morphology, immunohistochemistry helped us to reach a conclusive diagnosis for relevant therapy.

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收藏

页码：306 / 307

页数：2

相关论文

共 8 条

[1] Mediastinal mixed dendritic cell sarcoma with hybrid features [J].

Dillon, KM ;

Hill, CM ;

Cameron, CHS ;

Attanoos, RL ;

McCluggage, WG .

JOURNAL OF CLINICAL PATHOLOGY, 2002, 55 (10) :791-794

[2] Dendritic cell neoplasms: An overview [J].

Kairouz, Sebastien ;

Hashash, Jana ;

Kabbara, Wadih ;

Mchayleh, Wassim ;

Tabbara, Imad A. .

AMERICAN JOURNAL OF HEMATOLOGY, 2007, 82 (10) :924-928

[3] Tumours of histiocytes and accessory dendritic cells:: an immunohistochemical approach to classification from the International Lymphoma Study Group based on 61 cases [J].

Pileri, SA ;

Grogan, TM ;

Harris, NL ;

Banks, P ;

Campo, E ;

Chan, JKC ;

Favera, RD ;

Delsol, G ;

De Wolf-Peeters, C ;

Falini, B ;

Gascoyne, RD ;

Gaulard, P ;

Gatter, KC ;

Isaacson, PG ;

Jaffe, ES ;

Kluin, P ;

Knowles, DM ;

Mason, DY ;

Mori, S ;

Müller-Hermelink, HK ;

Piris, MA ;

Ralfkiaer, E ;

Stein, H ;

Su, IJ ;

Warnke, RA ;

Weiss, LM .

HISTOPATHOLOGY, 2002, 41 (01) :1-29

[4] CERVICAL FOLLICULAR DENDRITIC CELL SARCOMA: A CASE REPORT AND REVIEW OF THE LITERATURE [J].

Pizzi, M. ;

Ludwig, K. ;

Palazzolo, G. ;

Busatto, G. ;

Rettore, C. ;

Altavilla, G. .

INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY, 2011, 24 (02) :539-544

[5] Clinical and pathological features of follicular dendritic cell sarcoma of appendix: a case report [J].

Shen Dan-ping ;

Ni Xing-zhi ;

Yin Xiao-lu ;

Wu Zhi-yong .

CHINESE MEDICAL JOURNAL, 2009, 122 (13) :1595-1597

[6] Follicular dendritic cell sarcoma: a report of six cases and a review of the Chinese literature [J].

Wang, Haiwei ;

Su, Zhansan ;

Hu, Zhongliang ;

Wen, Jifang ;

Liu, Baoan .

DIAGNOSTIC PATHOLOGY, 2010, 5

[7]

Xie QM, 2008, INT J CLIN EXP PATHO, V1, P276

[8] Follicular dendritic cell sarcoma of small intestine with aberrant T-cell marker expression [J].

Yamada, Yosuke ;

Haga, Hironori ;

Hernandez, Mako ;

Kubota, Kanako C. ;

Orii, Fumika ;

Nagashima, Kazuo ;

Matsuno, Yoshihiro .

PATHOLOGY INTERNATIONAL, 2009, 59 (11) :809-812