Dynamical behaviour of fractional order tumor model with Caputo and conformable fractional derivative

被引:68
作者
Balci, Ercan [1 ]
Ozturk, Ilhan [1 ]
Kartal, Senol [2 ]
机构
[1] Erciyes Univ, Dept Math, TR-38039 Kayseri, Turkey
[2] Nevsehir Haci Bektas Veli Univ, Dept Sci & Math Educ, TR-50300 Nevsehir, Turkey
关键词
Tumor-immune interaction; Fractional order; Piecewise-constant arguments; Neimark-Sacker bifurcation; Conformable fractional derivative; DIFFERENTIAL-EQUATIONS; NONLINEAR DYNAMICS; STABILITY;
D O I
10.1016/j.chaos.2019.03.032
中图分类号
O1 [数学];
学科分类号
0701 ; 070101 ;
摘要
In this paper, tumor-immune system interaction has been considered by two fractional order models. The first and the second model consist of system of fractional order differential equations with Caputo and conformable fractional derivative respectively. First of all, the stability of the equilibrium points of the first model is studied. Then, a discretization process is applied to obtain a discrete version of the second model where conformable fractional derivative is taken into account. In discrete model, we analyze the stability of the equilibrium points and prove the existence of Neimark-Sacker bifurcation depending on the parameter sigma. Moreover, the dynamical behaviours of the models are compared with each other and we observe that the discrete version of conformable fractional order model exhibits chaotic behavior. Finally, numerical simulations are also presented to illustrate the analytical results. (C) 2019 Elsevier Ltd. All rights reserved.
引用
收藏
页码:43 / 51
页数:9
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