Porcine circovirus type 3 (PCV3) infection in grower pigs from a Thai farm suffering from porcine respiratory disease complex (PRDC)

被引：105

作者：

Kedkovid, Roongtham ^{[1
]}

Woonwong, Yonlayong ^{[1
]}

Arunorat, Jirapat ^{[1
]}

Sirisereewan, Chaitawat ^{[1
]}

Sangpratum, Nattaphong ^{[1
]}

Lumyai, Mongkol ^{[5
]}

Kesdangsakonwut, Sawang ^{[2
]}

Teankum, Komkrich ^{[2
]}

Jittimanee, Suphattra ^{[4
]}

Thanawongnuwech, Roongroje ^{[2
,3
]}

机构：

[1] Chulalongkorn Univ, Grad Program Vet Pathobiol, Fac Vet Sci, 39 Henri Dunant Rd, Bangkok 10330, Thailand

[2] Chulalongkorn Univ, Dept Vet Pathol, Fac Vet Sci, 39 Henri Dunant Rd, Bangkok 10330, Thailand

[3] Chulalongkorn Univ, EIDAs, Ctr Excellence Emerging Infect Dis Anim, Fac Vet Sci, 39 Henri Dunant Rd, Bangkok 10330, Thailand

[4] Khon Kaen Univ, Fac Vet Med, Dept Pathobiol, 123 Mittraphap Rd, Khon Kaen 40002, Thailand

[5] 1-34 Bangnathanee Bldg,Bangna Trad Rd, Bangkok 10260, Thailand

来源：

VETERINARY MICROBIOLOGY | 2018年 / 215卷

关键词：

Porcine circovirus type 3; Porcine respiratory disease complex; Thailand; GENETIC-CHARACTERIZATION; SYNDROME VIRUS;

D O I：

10.1016/j.vetmic.2018.01.004

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Porcine circovirus type 3 (PCV3) is a newly emerging virus with unknown pathogenesis. The major objective of this study was to investigate the presence of PCV3 in pigs from a farm in Thailand suffering from porcine respiratory disease complex (PRDC). Initially, a Thai PCV3 strain (PCV3/Thailand/PB01/17) was identified from a pig originated from a farm with PRDC problem during grower period and whole genome analysis showed that the Thai PCV3 shared highest nucleotide identity of 99.60% with the South Korean strain PCV3/KU-1602. The presence of PCV3 infection in PRDC-affected pigs was then investigated in this farm. Serum samples from clinically healthy pigs and pigs showing PRDC-related clinical signs during 5-18 weeks were used in PCV3 detection by PCR. The results showed that the PRDC-affected pigs exhibited higher prevalence of PCV3 infection and higher PCV3 titers comparing with the clinically healthy pigs. These results confirmed the presence of PCV3 in a Thai farm with PRDC problem. The pathogenesis of PCV3 on PRDC should be clarified in further studies.

引用

页码：71 / 76

页数：6