Facile syntheses of D-mannose hexa- and nonasaccharides:: the di- and trimer of the trisaccharide repeating unit of the cell-wall mannans of Epidermophyton floccosum, Trychophyton mentagrophytes, Microsporum canis and related species of Microsporum

A highly efficient strategy for the preparation Of D-mannose hexa- and nonasaccharides, the dimer and trimer of the alpha-D-Manp-(1 --> 6)-[alpha-D-Manp-(1 --> 2)-]D-Manp trisaccharide repeating unit of the cell-wall mannans from the fungi Epidermophyton flovcosum, Trychophyton mentagrophytes, Microsporum canis, ill. cookei and V racemosum, has been developed Using 1,2,6-tri-O-acetyl-3,4-di-O-benzoyl-alpha-D-mannopyranose (6) as the key synthon. (C) 2002 Elsevier Science Ltd. All rights reserved.