Catalyst-Free Synthesis of α,α-bis(4-Hydroxycoumarin-3-yl)toluene in Aqueous Media Under Microwave Irradiation

被引：39

作者：

Gong, Gui-Xia ^{[2
]}

Zhou, Jian-Feng ^{[1
,2
]}

An, Li-Tao ^{[1
]}

Duan, Xiu-Li ^{[1
]}

Ji, Shun-Jun ^{[2
]}

机构：

[1] Huaiyin Teachers Coll, Dept Chem, Jiangsu Key Lab Chem Low Dimens Mat, Huaian 223300, Peoples R China

[2] Suzhou Univ, Sch Chem & Chem Engn, Key Lab Organ Synth Jiangsu Prov, Suzhou 215006, Peoples R China

来源：

SYNTHETIC COMMUNICATIONS | 2009年 / 39卷 / 03期

关键词：

Aqueous media; aromatic aldehyde; alpha; alpha-bis(4-hydroxycoumarin-3-yl)toluene; 4-hydroxycoumarin; microwave irradiation; CLAISEN REARRANGEMENT; CONDENSATION; DERIVATIVES; WATER; INHIBITORS; SOLVENT;

D O I：

10.1080/00397910802398272

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient catalyst-free synthesis of alpha,alpha-bis(4-hydroxycoumarin-3-yl)toluene was performed by the reaction of 4-hydroxycoumarin with aromatic aldehydes in aqueous media under microwave irradiation. The reaction was completed in short reaction time of 8-10 min with high yields of 76-94, was environmental benign, and had easy workup. Their structures were confirmed by IR spectra, H-1 NMR, C-13 NMR, and elemental analysis.

引用

页码：497 / 505

页数：9

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[Anonymous], J MOL CATAL A

[2]

[Anonymous], EUR J MED CHEM

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