Advances in pediatric antimicrobial agents development

被引：3
|
作者：
Wood, James B. [1 ]
Cravens, Lauryn B. [2 ]
Creech, C. Buddy [2 ]
机构：
[1] Indiana Univ Sch Med, Div Pediat Infect Dis, Indianapolis, IN 46202 USA
[2] Vanderbilt Univ, Sch Med, Vanderbilt Vaccine Res Program, CCC 5319 Med Ctr North,1161 21st Ave South, Nashville, TN 37232 USA
来源：
CURRENT OPINION IN PEDIATRICS | 2019年 / 31卷 / 01期
关键词：
antimicrobials; drug development; multidrug-resistant organisms; PLEUROMUTILIN ANTIBIOTIC BC-3781; ACUTE BACTERIAL SKIN; DOUBLE-BLIND; CEFTAZIDIME-AVIBACTAM; TRACT-INFECTIONS; IN-VITRO; SAFETY; CEFTAROLINE; PHASE-3; PHARMACOKINETICS;
D O I：
10.1097/MOP.0000000000000713
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
Purpose of review Rising rates of multidrug-resistant organisms has necessitated the development of novel antimicrobials. In this review, we will highlight agents that have recently received licensure and those that are in clinical development. Recent findings In recent years, development of novel antimicrobial agents has accelerated. Although most studies have targeted the adult population, studies in pediatric patients are underway. Adequately powered clinical trials are needed to establish the safety and role of these new drugs. Summary The recent development of novel antimicrobials to combat multidrug-resistant organisms is encouraging; however, more studies in the pediatric population are needed.
引用
收藏
页码：135 / 143
页数：9
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