Cerebral sinus venous thrombosis in a subject with thyrotoxicosis and MTHFR gene polymorphism

被引:11
|
作者
Strada, Laura [1 ]
Gandolfo, Carlo [1 ]
Del Sette, Massimo [1 ]
机构
[1] Univ Genoa, Dept Neurosci Ophthalmol & Genet, I-16132 Genoa, Italy
关键词
Cerebral venous thrombosis; Tyrotoxicosis; Methylene-tetrahydro-folate-reductase (MTHFR); Heparin; Warfarin;
D O I
10.1007/s10072-008-0992-4
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
We report a case of cerebral venous thrombosis (CVT) due to tyrotoxicosis in a patient with methylene-tetrahydro-folate-reductase (MTHFR) gene polymorphism C677T, (genotype 677TT), in which discontinuation of intravenous heparin was followed by clinical and radiological worsening despite warfarin treatment. We discuss the relationship between CVT, MTHFR hyperthiroidism and anticoagulant therapy.
引用
收藏
页码:343 / 345
页数:3
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