Kras and Hras - what is the difference?

被引:9
作者
Berns, Anton [1 ,2 ]
机构
[1] Netherlands Canc Inst, Div Mol Genet, Ctr Biomed Genet, NL-1066 CX Amsterdam, Netherlands
[2] Netherlands Canc Inst, Canc Genom Ctr, NL-1066 CX Amsterdam, Netherlands
关键词
D O I
10.1038/ng1008-1149
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Kras, Hras or Nras mutations occur at varying frequencies across different tumors in humans for unknown reasons. a new study shows that, in mice, locus-specific regulatory elements determine whether mutations in Hras or Kras will predominate in lung and skin tumors.
引用
收藏
页码:1149 / 1150
页数:3
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