Activation Mechanism of a Signaling Protein at Atomic Resolution

被引:0
|
作者
Pontiggia, Francesco [1 ]
Pachov, Dimitar V. [1 ]
Clarkson, Michael W. [1 ]
Villali, Janice [1 ]
Hagan, Michael F. [2 ]
Pande, Vijay S. [3 ,4 ]
Kern, Dorothee [1 ,5 ]
机构
[1] Brandeis Univ, Dept Biochem, Waltham, MA 02254 USA
[2] Brandeis Univ, Dept Phys, Waltham, MA 02254 USA
[3] Stanford Univ, Dept Chem, Stanford, CA 94305 USA
[4] Stanford Univ, SIMBIOS, NIH Ctr Biomed Computat, Dept Bioengn, Stanford, CA 94305 USA
[5] Brandeis Univ, Howard Hughes Med Inst, Waltham, MA 02254 USA
关键词
D O I
10.1016/j.bpj.2014.11.2064
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
1889-Pos
引用
收藏
页码:376A / 376A
页数:1
相关论文
共 50 条
  • [1] Activation mechanism of a signaling protein at atomic resolution from advanced computations
    Ma, Liang
    Cui, Qiang
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2007, 129 (33) : 10261 - 10268
  • [2] Molecular Mechanism of Prion Protein Oligomerization at Atomic Resolution
    Schlepckow, Kai
    Schwalbe, Harald
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2013, 52 (38) : 10002 - 10005
  • [3] Free energy landscape of activation in a signalling protein at atomic resolution
    Pontiggia, F.
    Pachov, D. V.
    Clarkson, M. W.
    Villali, J.
    Hagan, M. F.
    Pande, V. S.
    Kern, D.
    NATURE COMMUNICATIONS, 2015, 6
  • [4] Free energy landscape of activation in a signalling protein at atomic resolution
    F. Pontiggia
    D.V. Pachov
    M.W. Clarkson
    J. Villali
    M.F. Hagan
    V.S. Pande
    D. Kern
    Nature Communications, 6
  • [5] Mechanism of CheA protein kinase activation in receptor signaling complexes
    Levit, MN
    Liu, Y
    Stock, JB
    BIOCHEMISTRY, 1999, 38 (20) : 6651 - 6658
  • [6] Protein structures at atomic resolution
    Dauter, Z
    MACROMOLECULAR CRYSTALLOGRAPHY, PT C, 2003, 368 : 288 - 337
  • [7] Protein Allostery at Atomic Resolution
    Strotz, Dean
    Orts, Julien
    Kadavath, Harindranath
    Friedmann, Michael
    Ghosh, Dhiman
    Olsson, Simon
    Chi, Celestine N.
    Pokharna, Aditya
    Güntert, Peter
    Vögeli, Beat
    Riek, Roland
    Advanced Materials, 2020, 132 (49): : 22316 - 22323
  • [8] Protein Allostery at Atomic Resolution
    Strotz, Dean
    Orts, Julien
    Kadavath, Harindranath
    Friedmann, Michael
    Ghosh, Dhiman
    Olsson, Simon
    Chi, Celestine N.
    Pokharna, Aditya
    Guentert, Peter
    Vogeli, Beat
    Riek, Roland
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2020, 59 (49) : 22132 - 22139
  • [9] Structure of the redox sensor domain of Azotobacter vinelandii NifL at atomic resolution:: Signaling, dimerization, and mechanism
    Key, Jason
    Hefti, Marco
    Purcell, Erin B.
    Moffat, Keith
    BIOCHEMISTRY, 2007, 46 (12) : 3614 - 3623
  • [10] Temporal resolution of protein signaling
    Anderson, Karen
    Sohl, Christal
    Luo, BeiBei
    Mo, Shunyan
    Kim, Youngjoo
    Apetri, Mihaela
    Lew, Erin
    Furdui, Cristina
    Schlessinger, Joseph
    FASEB JOURNAL, 2014, 28 (01):