AgNO2 as the NO Source for the Synthesis of Substituted Pyrazole N-Oxides from N-Propargylamines

被引：34

作者：

Yuan, Bingxiang ^{[1
]}

Zhang, Fuming ^{[1
]}

Li, Zhuomei ^{[2
]}

Yang, Shenghua ^{[1
]}

Yan, Rulong ^{[1
]}

机构：

[1] Lanzhou Univ, Dept Chem, Key Lab Nonferrous Met Chem & Resources Utilizt G, State Key Lab Appl Organ Chem, Lanzhou, Gansu, Peoples R China

[2] Lanzhou Univ, Middle Sch, Lanzhou, Gansu, Peoples R China

来源：

ORGANIC LETTERS | 2016年 / 18卷 / 22期

基金：

中国国家自然科学基金;

关键词：

C BOND-CLEAVAGE; STEREOSELECTIVE NITRATION; CATALYZED NITROGENATION; EFFICIENT SYNTHESIS; SODIUM-AZIDE; H BOND; NITRILES; OLEFINS; DERIVATIVES; INHIBITORS;

D O I：

10.1021/acs.orglett.6b03021

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A straightforward method for synthesizing the pyrazole N-oxides from N-propargylamines and AgNO2, through oxidation/cyclization reaction had been developed. AgNO2, was used as the NO source for the first time to synthesize pyrazole N-oxides. Various substituted groups on N-propargylamines proceeded smoothly, and the desired products were obtained in good yields.

引用

页码：5928 / 5931

页数：4

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