Quality control assessment of human immunodeficiency virus type 2 (HIV-2) viral load quantification assays:: Results from an international collaboration on HIV-2 infection in 2006

被引：33

作者：

Damond, Florence ^{[1
]}

Benard, Antoine ^{[2
]}

Ruelle, Jean ^{[3
]}

Alabi, Abraham ^{[4
]}

Kupfer, Bernd ^{[5
]}

Gomes, Perpetua ^{[7
]}

Rodes, Berta ^{[6
]}

Albert, Jan ^{[8
,9
]}

Boeni, Juerg ^{[10
]}

Garson, Jeremy ^{[11
]}

Ferns, Bridget ^{[11
]}

Matheron, Sophie ^{[12
]}

Chene, Genevieve ^{[2
]}

Vezinet, Francoise Brun ^{[1
]}

机构：

[1] Hop Bichat Claude Bernard, Virol Lab, APHP, F-75018 Paris, France

[2] Univ Bordeaux 2, INSERM, U897, ISPED, F-33076 Bordeaux, France

[3] Catholic Univ Louvain, AIDS Reference Lab, B-1348 Louvain, Belgium

[4] MRC Labs, Banjul, Gambia

[5] Inst Virol, Bonn, Germany

[6] Hosp Carlos III, Dept Infect Dis, Madrid, Spain

[7] CHLO Hosp Egas Moniz, Mol Biol Lab, Lisbon, Portugal

[8] Swedish Inst Infect Dis Control, Dept Virol, Solna, Sweden

[9] Karolinska Inst, Dept Microbiol Tumor & Cell Biol, Stockholm, Sweden

[10] Swiss HIV Cohort Study, Zurich, Switzerland

[11] UCL Royal Free & Univ Coll Med Sch, Ctr Virol, London WC1E 6BT, England

[12] Hop Bichat Claude Bernard, Serv Malad Infect & Trop, APHP, F-75877 Paris 18, France

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2008年 / 46卷 / 06期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1128/JCM.00126-08

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Human immunodeficiency virus type 2 (HIV-2) RNA quantification assays used in nine laboratories of the ACHIEV2E (A Collaboration on HIV-2 Infection) study group were evaluated. In a blinded experimental design, laboratories quantified three series of aliquots of an HIV-2 subtype A strain, each at a different theoretical viral load. Quantification varied between laboratories, and international standardization of quantification assays is strongly needed.

引用

页码：2088 / 2091

页数：4

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