Thermodynamics of Fluconazole Solubility in Various Solvents at Different Temperatures

被引：24

作者：

Bhesaniya, Kapil ^{[1
]}

Nandha, Kajal ^{[1
]}

Baluja, Shipra ^{[1
]}

机构：

[1] Saurashtra Univ, Dept Chem, Phys Chem Lab, Rajkot 360005, Gujarat, India

来源：

JOURNAL OF CHEMICAL AND ENGINEERING DATA | 2014年 / 59卷 / 03期

关键词：

Atmospheric temperature - Chlorine compounds - Atmospheric pressure;

D O I：

10.1021/je4010257

中图分类号：

O414.1 [热力学];

学科分类号：

摘要：

The solubility of Fluconazole in pure methanol, ethanol, propan-1-ol, butane-1-ol, chloroform, tetrahydrofuran, and 1,4-dioxane was measured by gravimetric method over a temperature range (298.15 to 323.15) K at atmospheric pressure. The solubility increases nonlinearly with temperature in all seven solvents. The experimental data were correlated with a modified Apelblat equation. The calculated results show good agreement with the experimental data.

引用

页码：649 / 652

页数：4

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