Gamma irradiation irradiation enhances biological activities of mulberry leaf extract

被引：7

作者：

Cho, Byoung-Ok ^{[1
,2
]}

Che, Denis Nchang ^{[2
]}

Yin, Hong-Hua ^{[1
]}

Jang, Seon-Il ^{[1
,2
,3
]}

机构：

[1] Ato Q&A Corp, Res Inst, Jeonju 55069, South Korea

[2] Jeonju Univ, Dept Hlth Care & Sci, Jeonju 55069, South Korea

[3] Jeonju Univ, Agri Bio Inst, Jeonju 55069, South Korea

来源：

RADIATION PHYSICS AND CHEMISTRY | 2017年 / 133卷

关键词：

Mulberry leaf; Gamma irradiation; Oxidative stress; Anti-inflammation; Tyrosinase inhibition; NF-KAPPA-B; ANTIOXIDANT ACTIVITY; ANTIINFLAMMATORY ACTIVITY; OXIDATIVE STRESS; FREE-RADICALS; BLACK PEPPER; L; CAPACITY; FRUITS; ACID;

D O I：

10.1016/j.radphyschem.2016.11.013

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The purpose of this study was to investigate the influence of irradiation on the anti-oxidative, anti-inflammatory and whitening effects of mulberry leaf extract. This was done by comparing the phenolic contents; 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging effects; 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonicacid) (ABTS) radical scavenging effects; in vitro tyrosinase inhibitory effects and the production of IL-6, TNF-alpha, PGE(2), and NO in lipopolysaccharide-stimulated RAW264.7 macrophages and the production of IL-6 and TNF-alpha in phorbol 12-myristate 13-acetate plus calcium ionophore A23187-stimulated HMC-1 cells, respectively. The results showed that irradiated mulberry leaf extract possesses more anti-oxidant, anti-inflammatory, and tyrosinase inhibitory activities than their non-irradiated counterpart, probably due to increase in phenolic contents induced by gamma irradiation at dose of 10kGy. This research stresses on the importance of irradiation in functional foods.

引用

页码：21 / 27

页数：7

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