Disseminated zygomycosis due to Mycocladus corymbifera with cutaneous and cerebral involvement

被引:3
作者
Schofield, Clare [1 ]
Stern, Alexander [2 ]
Jevtic, Andrew [1 ]
机构
[1] Royal Hobart Hosp, Dept Dermatol, Hobart, Tas 7000, Australia
[2] Royal Hobart Hosp, Dept Neurosurg, Hobart, Tas 7000, Australia
关键词
Mucorales; mucormycosis; Mycocladus corymbifera; zygomycosis;
D O I
10.1111/j.1440-0960.2011.00752.x
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Fungal infections caused by zygomycetes are important and potentially life threatening infections. These opportunistic moulds have been increasingly implicated in human disease and are most frequently seen in immune compromised patients. We report a case of disseminated infection with Mycocladus corymbifera involving the brain, lungs, kidneys and skin in a 16-year-old patient with acute lymphoblastic leukaemia. The skin lesions played a significant role in the diagnosis of mucormycosis. These infections have an exceedingly high mortality rate and early recognition of cutaneous lesions is essential to successful management.
引用
收藏
页码:E8 / E11
页数:4
相关论文
共 12 条
[1]   Spectrum of Zygomycete Species Identified in Clinically Significant Specimens in the United States [J].
Alvarez, E. ;
Sutton, D. A. ;
Cano, J. ;
Fothergill, A. W. ;
Stchigel, A. ;
Rinaldi, M. G. ;
Guarro, J. .
JOURNAL OF CLINICAL MICROBIOLOGY, 2009, 47 (06) :1650-1656
[2]   Outbreaks of zygomycosis in hospitals [J].
Antoniadou, A. .
CLINICAL MICROBIOLOGY AND INFECTION, 2009, 15 :55-59
[3]  
Chandra Suresh, 2002, Australas J Dermatol, V43, P39, DOI 10.1046/j.1440-0960.2002.00550.x
[4]  
Hocker Thomas Lewis, 2010, Dermatol Online J, V16, P3
[5]   Zygomycosis in a Tertiary-Care Cancer Center in the era of Aspergillus-active antifungal therapy:: A case-control observational study of 27 recent cases [J].
Kontoyiannis, DP ;
Lionakis, MS ;
Lewis, RE ;
Chamilos, G ;
Healy, M ;
Perego, C ;
Safdar, A ;
Kantarjian, H ;
Champlin, R ;
Walsh, TJ ;
Raad, II .
JOURNAL OF INFECTIOUS DISEASES, 2005, 191 (08) :1350-1360
[6]   Primary cutaneous mucormycosis in an immunocompetent host: Report of a case [J].
Kumar, A ;
Khilnani, GC ;
Aggarwal, S ;
Kumar, S ;
Banerjee, U ;
Xess, I .
SURGERY TODAY, 2003, 33 (04) :319-322
[7]   Clinical presentation of zygomycosis [J].
Mantadakis, E. ;
Samonis, G. .
CLINICAL MICROBIOLOGY AND INFECTION, 2009, 15 :15-20
[8]   Epidemiology and outcome of zygomycosis: A review of 929 reported cases [J].
Roden, MM ;
Zaoutis, TE ;
Buchanan, WL ;
Knudsen, TA ;
Sarkisova, TA ;
Schaufele, RL ;
Sein, M ;
Sein, T ;
Chiou, CC ;
Chu, JH ;
Kontoyiannis, DP ;
Walsh, TJ .
CLINICAL INFECTIOUS DISEASES, 2005, 41 (05) :634-653
[9]   Buffs-eye cutaneous infarct of zygomycosis: A bedside diagnosis confirmed by touch preparation [J].
Rubin, AI ;
Grossman, ME .
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2004, 51 (06) :996-1001
[10]   Disseminated zygomycosis with involvement of the central nervous system [J].
Skiada, A. ;
Vrana, L. ;
Polychronopoulou, H. ;
Prodromou, P. ;
Chantzis, A. ;
Tofas, P. ;
Daikos, G. L. .
CLINICAL MICROBIOLOGY AND INFECTION, 2009, 15 :46-49