Dairy products intake and the risk of incident cataracts surgery in an elderly Mediterranean population: results from the PREDIMED study

被引：10

作者：

Camacho-Barcia, Lucia ^{[1
,2
]}

Bullo, Monica ^{[1
,2
]}

Garcia-Gavilan, Jesus F. ^{[1
,2
]}

Martinez-Gonzalez, Miguel A. ^{[2
,3
]}

Corella, Dolores ^{[2
,4
]}

Estruch, Ramon ^{[2
,5
]}

Fito, Montse ^{[2
,6
]}

Gomez-Gracia, Enrique ^{[2
,7
]}

Aros, Fernando ^{[2
,8
]}

Fiol, Miquel ^{[2
,9
]}

Santos-Lozano, Jose M. ^{[2
,10
]}

Serra-Majem, Lluis ^{[2
,11
]}

Pinto, Xavier ^{[2
,12
]}

Basora, Josep ^{[1
]}

Toledo, Estefania ^{[2
,13
]}

Munoz, Miguel A. ^{[2
,14
,15
]}

Zanon-Moreno, Vicente ^{[4
,16
,17
]}

Garcia-Layana, Alfredo ^{[2
,18
]}

Salas-Salvado, Jordi ^{[1
,2
]}

机构：

[1] Univ Rovira & Virgili, Univ Hosp St Joan de Reus, Fac Med & Hlth Sci, Human Nutr Unit,Biochem & Biotechnol Dept,IISPV, St St Llorenc 21, Reus 43201, Spain

[2] Inst Hlth Carlos III, CIBERobn Physiopathol Obes & Nutr, Madrid, Spain

[3] Univ Navarra, Sch Med, Dept Prevent Med & Publ Hlth, Pamplona, Spain

[4] Univ Valencia, Dept Prevent Med, Valencia, Spain

[5] Univ Barcelona, Hosp Clin, August Pi & Sunyer Inst Biomed Res IDIBAPS, Dept Internal Med, Barcelona, Spain

[6] Hosp del Mar, Med Res Inst, Cardiovasc Risk & Nutr, Regicor Study Grp, Barcelona Biomed Res Pk, Barcelona, Spain

[7] Univ Malaga, Dept Prevent Med, Malaga, Spain

[8] Univ Hosp Araba, Dept Cardiol, Vitoria, Spain

[9] Univ Hosp Son Dureta, Dept Cardiol, Palma De Mallorca, Spain

[10] San Pablo Hlth Ctr, Dept Family Med, Seville, Spain

[11] Univ Las Palmas Gran Canaria, Res Inst Biomed & Hlth Sci, Las Palmas Gran Canaria, Spain

[12] Univ Hosp Bellvitge, Internal Med, Lipids & Vasc Risk Unit, Barcelona, Spain

[13] Natl Hlth Serv Osasunbidea, Emergency Dept, Navarras Hosp Complex, Pamplona, Spain

[14] Inst Catala Salut, Primary Hlth Care Div, Barcelona, Spain

[15] Idiap Jordi Gol, Barcelona, Spain

[16] Santiago Grisolia Valencia, Ophthalm Res Unit, Santiago, Spain

[17] ISCIII, Red Temat Patol Ocular OFTARED, Madrid, Spain

[18] Univ Navarra, Dept Ophthalmol, Pamplona, Spain

来源：

EUROPEAN JOURNAL OF NUTRITION | 2019年 / 58卷 / 02期

关键词：

Cataracts; Dairy; Yogurt; Epidemiology; PREDIMED; AGE-RELATED CATARACT; MILK; CONSUMPTION; METAANALYSIS; ASSOCIATION; CALCIUM; YOGURT; STRESS; DIET;

D O I：

10.1007/s00394-018-1647-8

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 ;

摘要：

ProposalThe aim of this study was to examine the association between the consumption of total and specific types of dairy products and the risk of incident cataracts in an elderly Mediterranean population at high cardiovascular risk.MethodsWe prospectively analyzed 5860 subjects from the PREvencion con DIeta MEDiterranea (PREDIMED) Study. The time to cataract surgery was calculated as the time between recruitment and the date of the surgery, last visit of the follow-up, date of death, or until the end of the study. Dairy products intake was assessed using validated food frequency questionnaires. We used Cox proportional hazard regression to assess the risk of cataract surgery according to average dietary energy-adjusted total dairy products, milk, yogurt and cheese consumption.ResultsWe documented a total of 768 new cataract events after a median of 5.6years of follow-up. Subjects in the second [hazard ratio (HR) 0.62; 95% CI 0.52, 0.74] and third tertile (HR: 0.71; 95% CI 0.60, 0.85) of skimmed yogurt intake had a significantly lower risk of cataracts after adjusting for potential confounders. No significant associations were observed for total dairy products, whole and skimmed milk, whole yogurt and cheese consumption.ConclusionThe intake of skimmed yogurt was associated with a reduced risk of cataracts in an elderly Mediterranean population with high cardiovascular risk. No significant associations were observed for other type of dairy product.Clinical Trial registrationInternational Standard Randomized Controlled Trial Number (ISRCTN): 35739639. Registration date: 5 October 2005.

引用

页码：619 / 627

页数：9

共 35 条

[11] Dairy product consumption and risk of type 2 diabetes in an elderly Spanish Mediterranean population at high cardiovascular risk [J].