Moving towards IMPROVED drug-free remission

被引:1
作者
Bykerk, Vivian P. [1 ,2 ]
机构
[1] Weill Cornell Med Coll, New York, NY 10065 USA
[2] Hosp Special Surg, Inflammatory Arthrit Ctr, 535 E 70th St, New York, NY 10021 USA
基金
加拿大健康研究院; 美国国家卫生研究院;
关键词
RHEUMATOID-ARTHRITIS;
D O I
10.1038/nrrheum.2018.49
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The newly published 5-year outcomes of the IMPROVED trial demonstrate the feasibility of achieving long-term drug-free remission in early rheumatoid arthritis (RA). These findings raise the bar and support the use of a remission induction and maintenance approach, particularly in patients presenting with early joint inflammation consistent with early RA.
引用
收藏
页码:193 / 194
页数:2
相关论文
共 50 条
  • [31] Identification of differential co-expressed gene networks in early rheumatoid arthritis achieving sustained drug-free remission after treatment with a tocilizumab-based or methotrexate-based strategy
    Teitsma, Xavier M.
    Jacobs, Johannes W. G.
    Mokry, Michal
    Borm, Michelle E. A.
    Petho-Schramm, Attila
    van Laar, Jacob M.
    Bijlsma, Johannes W. J.
    Lafeber, Floris P. J.
    ARTHRITIS RESEARCH & THERAPY, 2017, 19
  • [32] Identification of differential co-expressed gene networks in early rheumatoid arthritis achieving sustained drug-free remission after treatment with a tocilizumab-based or methotrexate-based strategy
    Xavier M. Teitsma
    Johannes W. G. Jacobs
    Michal Mokry
    Michelle E. A. Borm
    Attila Pethö-Schramm
    Jacob M. van Laar
    Johannes W. J. Bijlsma
    Floris P. J. Lafeber
    Arthritis Research & Therapy, 19
  • [33] Baseline metabolic profiles of early rheumatoid arthritis patients achieving sustained drug-free remission after initiating treat-to-target tocilizumab, methotrexate, or the combination: insights from systems biology
    Teitsma, Xavier M.
    Yang, Wei
    Jacobs, Johannes W. G.
    Petho-Schramm, Attila
    Borm, Michelle E. A.
    Harms, Amy C.
    Hankemeier, Thomas
    van Laar, Jacob M.
    Bijlsma, Johannes W. J.
    Lafeber, Floris P. J. G.
    ARTHRITIS RESEARCH & THERAPY, 2018, 20
  • [34] Does the presence of magnetic resonance imaging-detected osteitis at diagnosis with rheumatoid arthritis lower the risk for achieving disease-modifying antirheumatic drug-free sustained remission: results of a longitudinal study
    Burgers, L. E.
    Boeters, D. M.
    Reijnierse, M.
    van der Helm-van Mil, A. H. M.
    ARTHRITIS RESEARCH & THERAPY, 2018, 20
  • [35] Does the presence of magnetic resonance imaging-detected osteitis at diagnosis with rheumatoid arthritis lower the risk for achieving disease-modifying antirheumatic drug-free sustained remission: results of a longitudinal study
    L. E. Burgers
    D. M. Boeters
    M. Reijnierse
    A. H. M. van der Helm-van Mil
    Arthritis Research & Therapy, 20
  • [36] Exploration and Evaluation of Therapeutic Efficacy of Drug-Free Macromolecular Therapeutics in Collagen-Induced Rheumatoid Arthritis Mouse Model
    Wang, Jiawei
    Li, Yachao
    Li, Lian
    Yang, Jiyuan
    Kopecek, Jindrich
    MACROMOLECULAR BIOSCIENCE, 2020, 20 (05)
  • [37] An Analysis of the Biological Disease-modifying Antirheumatic Drug-free Condition of Adalimumab-treated Rheumatoid Arthritis Patients
    Ito, Satoshi
    Kobayashi, Daisuke
    Hasegawa, Eriko
    Takai, Chinatsu
    Nemoto, Tetsuya
    Lee, Hyunho
    Abe, Asami
    Otani, Hiroshi
    Ishikawa, Hajime
    Murasawa, Akira
    Narita, Ichiei
    Nakazono, Kiyoshi
    INTERNAL MEDICINE, 2019, 58 (04) : 511 - 519
  • [38] Drug free REmission/low disease activity after cessation of tocilizumab (Actemra) Monotherapy (DREAM) study
    Nishimoto, Norihiro
    Amano, Koichi
    Hirabayashi, Yasuhiko
    Horiuchi, Takahiko
    Ishii, Tomonori
    Iwahashi, Mitsuhiro
    Iwamoto, Masahiro
    Kohsaka, Hitoshi
    Kondo, Masakazu
    Matsubara, Tsukasa
    Mimura, Toshihide
    Miyahara, Hisaaki
    Ohta, Shuji
    Saeki, Yukihiko
    Saito, Kazuyoshi
    Sano, Hajime
    Takasugi, Kiyoshi
    Takeuchi, Tsutomu
    Tohma, Shigeto
    Tsuru, Tomomi
    Ueki, Yukitaka
    Yamana, Jiro
    Hashimoto, Jun
    Matsutani, Takaji
    Murakami, Miho
    Takagi, Nobuhiro
    MODERN RHEUMATOLOGY, 2014, 24 (01) : 17 - 25
  • [39] The long-term observation of patients with rheumatoid arthritis who achieved a biological disease-modifying antirheumatic drug-free condition with adalimumab
    Ito, Satoshi
    Sakai, Shunsuke
    Kurosawa, Yoichi
    Kobayashi, Daisuke
    Okabayashi, Ryo
    Abe, Asami
    Otani, Hiroshi
    Nakazono, Kiyoshi
    Murasawa, Akira
    Narita, Ichiei
    Ishikawa, Hajime
    MODERN RHEUMATOLOGY, 2021, 31 (04) : 919 - 923
  • [40] Moving the Goalpost Toward Remission: The Case for Combination Immunomodulatory Therapies in Psoriatic Arthritis
    Scher, Jose U.
    Ogdie, Alexis
    Merola, Joseph F.
    Ritchlin, Christopher
    ARTHRITIS & RHEUMATOLOGY, 2021, 73 (09) : 1574 - 1578