Haemoptysis in adults: a 5-year study using the French nationwide hospital administrative database

被引:105
作者
Abdulmalak, Caroline [1 ]
Cottenet, Jonathan [2 ]
Beltramo, Guillaume [1 ]
Georges, Marjolaine [1 ,3 ]
Camus, Philippe [1 ,3 ,4 ]
Bonniaud, Philippe [1 ,3 ,4 ]
Quantin, Catherine [2 ,3 ,4 ]
机构
[1] Ctr Hosp Univ Bocage, Serv Pneumol & Soins Intensifs Resp, F-21079 Dijon, France
[2] Univ Hosp, Dept Med Informat, Dijon, France
[3] Univ Burgundy, Fac Med & Pharm, Dijon, France
[4] INSERM, U866, Dijon, France
关键词
BRONCHIAL ARTERY EMBOLIZATION; CRYPTOGENIC HEMOPTYSIS; FEBRILE CONVULSIONS; LUNG-CANCER; MORTALITY; FRANCE; STROKE; TEMPERATURE; MANAGEMENT; INFARCTION;
D O I
10.1183/09031936.00218214
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Haemoptysis is a serious symptom with various aetiologies. Our aim was to define the aetiologies, outcomes and associations with lung cancer in the entire population of a high-income country. This retrospective multicentre study was based on the French nationwide hospital medical information database collected over 5 years (2008-2012). We analysed haemoptysis incidence, aetiologies, geographical and seasonal distribution and mortality. We studied recurrence, association with lung cancer and mortality in a 3-year follow-up analysis. Each year, similar to 15000 adult patients (mean age 62 years, male/female ratio 2/1) were admitted for haemoptysis or had haemoptysis as a complication of their hospital stay, representing 0.2% of all hospitalised patients. Haemoptysis was cryptogenic in 50% of cases. The main aetiologies were respiratory infections (22%), lung cancer (17.4%), bronchiectasis (6.8%), pulmonary oedema (4.2%), anticoagulants (3.5%), tuberculosis (2.7%), pulmonary embolism (2.6%) and aspergillosis (1.1%). Among incident cases, the 3-year recurrence rate was 16.3%. Of the initial cryptogenic haemoptysis patients, 4% were diagnosed with lung cancer within 3 years. Mortality rates during the first stay and at 1 and 3 years were 9.2%, 21.6% and 27%, respectively. This is the first epidemiological study analysing haemoptysis and its outcomes in an entire population. Haemoptysis is a life-threatening symptom unveiling potentially life-threatening underlying conditions.
引用
收藏
页码:503 / 511
页数:9
相关论文
共 29 条
[1]   Haemoptysis: aetiology, evaluation amd outcome - a prospective study in a third-world country [J].
Abal, AT ;
Nair, PC ;
Cherian, J .
RESPIRATORY MEDICINE, 2001, 95 (07) :548-552
[2]   How accurate is the reporting of stroke in hospital discharge data? A pilot validation study using a population-based stroke registry as control [J].
Aboa-Eboule, Corine ;
Mengue, Dominique ;
Benzenine, Eric ;
Hommel, Marc ;
Giroud, Maurice ;
Bejot, Yannick ;
Quantin, Catherine .
JOURNAL OF NEUROLOGY, 2013, 260 (02) :605-613
[3]   Seasonal variation in cryptogenic and noncryptogenic hemoptysis hospitalizations in France [J].
Boulay, F ;
Berthier, F ;
Sisteron, O ;
Grendreike, Y ;
Blaive, B .
CHEST, 2000, 118 (02) :440-444
[4]   Immediate and Long-term Results of Bronchial Artery Embolization for Hemoptysis Due to Benign Versus Malignant Pulmonary Diseases [J].
Chen, Jie ;
Chen, Liang-an ;
Liang, Zhi-Xin ;
Li, Chun-Sun ;
Tian, Qing ;
Yang, Zhen ;
Jiang, Yan-Wen ;
She, Dan-Yang .
AMERICAN JOURNAL OF THE MEDICAL SCIENCES, 2014, 348 (03) :204-209
[5]   Cryptogenic Hemoptysis in Chronic Obstructive Pulmonary Disease: Characteristics and Outcome [J].
Delage, Antoine ;
Tillie-Leblond, Isabelle ;
Cavestri, Beatrice ;
Wallaert, Benoit ;
Marquette, Charles-Hugo .
RESPIRATION, 2010, 80 (05) :387-392
[6]   PROGNOSIS IN IDIOPATHIC HEMOPTYSIS [J].
DOUGLASS, BE ;
CARR, DT .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1952, 150 (08) :764-765
[7]   Early Prediction of In-Hospital Mortality of Patients with Hemoptysis: An Approach to Defining Severe Hemoptysis [J].
Fartoukh, Muriel ;
Khoshnood, Babak ;
Parrot, Antoine ;
Khalil, Antoine ;
Carette, Marie-France ;
Stoclin, Annabelle ;
Mayaud, Charles ;
Cadranel, Jacques ;
Ancel, Pierre Yves .
RESPIRATION, 2012, 83 (02) :106-114
[8]   Hemoptysis:: a retrospective analysis of 108 cases [J].
Fidan, A ;
Özdogan, S ;
Oruç, Ö ;
Salepçi, B ;
Öcal, Z ;
Çaglayan, B .
RESPIRATORY MEDICINE, 2002, 96 (09) :677-680
[9]   Results of Bronchial Artery Embolization for the Treatment of Hemoptysis Caused by Neoplasm [J].
Garcia-Olive, Ignasi ;
Sanz-Santos, Jose ;
Centeno, Carmen ;
Andreo, Felipe ;
Munoz-Ferrer, Aida ;
Serra, Pere ;
Sampere, Jaume ;
Maria Michavila, Josep ;
Muchart, Jordi ;
Ruiz Manzano, Juan .
JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY, 2014, 25 (02) :221-228
[10]   Comparison of rehospitalization rates in France and the United States [J].
Gusmano, Michael ;
Rodwin, Victor ;
Weisz, Daniel ;
Cottenet, Jonathan ;
Quantin, Catherine .
JOURNAL OF HEALTH SERVICES RESEARCH & POLICY, 2015, 20 (01) :18-25