Study of compliance with a new, targeted antenatal D immunization prevention programme in Denmark

被引：10

作者：

Damkjaer, M. B. ^{[1
]}

Perslev, A.

Clausen, F. B. ^{[2
]}

Dziegiel, M. H. ^{[2
]}

Jorgensen, F. S. ^{[1
]}

机构：

[1] Copenhagen Univ Hosp, Hvidovre Hosp, Dept Obstet & Gynecol, Fetal Med Unit, Copenhagen, Denmark

[2] Copenhagen Univ Hosp, Rigshosp, Dept Clin Immunol, Copenhagen, Denmark

来源：

VOX SANGUINIS | 2012年 / 103卷 / 02期

关键词：

antenatal prophylaxis; cell-free fetal DNA; compliance; RHD genotyping; HEMOLYTIC-DISEASE; NEWBORN; FETUS;

D O I：

10.1111/j.1423-0410.2012.01602.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Background and Objectives A targeted routine antenatal anti-D prophylaxis programme was implemented in Denmark where anti-D immunoglobulin is given based on the result from noninvasive antenatal screening for fetal RHD. Our objective was to evaluate compliance with this new programme right after its initiation. Materials and Methods We examined the treatment outcome of 239 D-negative pregnant women who gave birth at our hospital between June and September 2010. Results The majority of these women (90%) underwent antenatal RHD screening, 86% of the women who were recommended antenatal prophylaxis received anti-D, and 99% of the women who delivered RhD-positive infants received postnatal anti-D. Conclusion These compliance results are acceptable as they were obtained only a few months after the initiation of the new prophylaxis regime. However, suggestions to further improve compliance are presented.

引用

页码：145 / 149

页数：5

共 6 条

[1]

[Anonymous], ANTI D ADM PREGNANCY

[2]

Brot C, 2009, ANBEFALINGER SVANGRE

[3] Report of the first nationally implemented clinical routine screening for fetal RHD in D- pregnant women to ascertain the requirement for antenatal RhD prophylaxis [J].