The Genetic Basis of Addictive Disorders

被引：155
作者：
Ducci, Francesca [2 ]
Goldman, David [1 ]
机构：
[1] NIAAA, Neurogenet Lab, NIH, Rockville, MD 20852 USA
[2] Kings Coll London, Inst Psychiat, London SE5 8AF, England
来源：
PSYCHIATRIC CLINICS OF NORTH AMERICA | 2012年 / 35卷 / 02期
关键词：
Substance use disorder; Heritability; MAOA; COMT; HTR2B; CATECHOL-O-METHYLTRANSFERASE; GENOME-WIDE ASSOCIATION; SEROTONIN TRANSPORTER GENE; SUBSTANCE USE DISORDERS; ENVIRONMENTAL RISK-FACTORS; POPULATION-BASED SAMPLE; ANTISOCIAL PERSONALITY-DISORDER; POSTTRAUMATIC-STRESS-DISORDER; NATIONAL EPIDEMIOLOGIC SURVEY; SUBSEQUENT ALCOHOL-USE;
D O I：
10.1016/j.psc.2012.03.010
中图分类号：
R749 [精神病学];
学科分类号：
100205 ;
摘要：
The authors review genetic factors moderating vulnerability to addictions: heritability and mode of inheritance, developmental changes across the lifespan of genetic and environmental influences, shared and unshared inheritance, interplay between genetic and environmental factors, gene identification via candidate genes and genome-wide approaches, and the role of rare and common genetic variants in addiction.
引用
收藏
页码：495 / +
页数：26
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