Preparation and Chiral Separation of a Novel Immobilized Cellulose-Based Chiral Stationary Phase in High-Performance Liquid Chromatography

被引：9

作者：

Peng, Gui Ming ^{[1
]}

Wu, Su Qin ^{[1
]}

Fang, Zhi Li ^{[1
]}

Zhang, Wei Guang ^{[1
]}

Zhang, Zhen Bin ^{[1
]}

Fan, Jun ^{[1
]}

Zheng, Sheng Run ^{[1
]}

Wu, Shang Sen ^{[1
]}

Ng, Siu Choon ^{[1
,2
]}

机构：

[1] S China Normal Univ, Sch Chem & Environm, Guangzhou 510006, Guangdong, Peoples R China

[2] Nanyang Technol Univ, Div Chem & Biomol Engn, Singapore 637459, Singapore

来源：

JOURNAL OF CHROMATOGRAPHIC SCIENCE | 2012年 / 50卷 / 06期

关键词：

SILICA-GEL; POLYSACCHARIDE DERIVATIVES; SOLVENT VERSATILITY; BETA-CYCLODEXTRIN; PACKING MATERIALS; RESOLUTION; ENANTIOMERS; HPLC; DISCRIMINATION; AMYLOSE;

D O I：

10.1093/chromsci/bms047

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The chiral selector 6-azido-2, 3-di(p-chlorophenylcarbamoylated) cellulose was synthesized and further chemically immobilized onto 5-mm amino functionalized spherical porous silica gel. It was used as chiral stationary phase in high-performance liquid chromatography. Thirty racemates were successfully separated into enantiomers in either normal phase mode or reversed-phase mode. Good reproducibility and stability of the chiral stationary phase have been demonstrated. © The Author [2012].

引用

页码：516 / 522

页数：7

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