Preparation and Chiral Separation of a Novel Immobilized Cellulose-Based Chiral Stationary Phase in High-Performance Liquid Chromatography

被引：9
|
作者：
Peng, Gui Ming [1 ]
Wu, Su Qin [1 ]
Fang, Zhi Li [1 ]
Zhang, Wei Guang [1 ]
Zhang, Zhen Bin [1 ]
Fan, Jun [1 ]
Zheng, Sheng Run [1 ]
Wu, Shang Sen [1 ]
Ng, Siu Choon [1 ,2 ]
机构：
[1] S China Normal Univ, Sch Chem & Environm, Guangzhou 510006, Guangdong, Peoples R China
[2] Nanyang Technol Univ, Div Chem & Biomol Engn, Singapore 637459, Singapore
来源：
JOURNAL OF CHROMATOGRAPHIC SCIENCE | 2012年 / 50卷 / 06期
关键词：
SILICA-GEL; POLYSACCHARIDE DERIVATIVES; SOLVENT VERSATILITY; BETA-CYCLODEXTRIN; PACKING MATERIALS; RESOLUTION; ENANTIOMERS; HPLC; DISCRIMINATION; AMYLOSE;
D O I：
10.1093/chromsci/bms047
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
The chiral selector 6-azido-2, 3-di(p-chlorophenylcarbamoylated) cellulose was synthesized and further chemically immobilized onto 5-mm amino functionalized spherical porous silica gel. It was used as chiral stationary phase in high-performance liquid chromatography. Thirty racemates were successfully separated into enantiomers in either normal phase mode or reversed-phase mode. Good reproducibility and stability of the chiral stationary phase have been demonstrated. © The Author [2012].
引用
收藏
页码：516 / 522
页数：7
相关论文
共 50 条
  • [1] High-performance liquid chromatography of imine stereoisomers on cellulose-based chiral stationary phases
    Willems, JGH
    Duchateau, ALL
    Zwanenburg, B
    CHIRALITY, 1997, 9 (08) : 727 - 731
  • [2] RESOLUTION OF CHIRAL SULFUR-COMPOUNDS ON A CELLULOSE-BASED HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC CHIRAL STATIONARY PHASE
    WAINER, IW
    ALEMBIK, MC
    JOHNSON, CR
    JOURNAL OF CHROMATOGRAPHY, 1986, 361 : 374 - 378
  • [3] High-performance liquid chromatography separation of glycerol derivatives on a chiral stationary phase
    Bugla, J
    Wandzik, I
    Szeja, W
    ACTA CHROMATOGRAPHICA, 2005, 15 : 173 - 182
  • [4] Stereoselective HPLC separation of alvimopan on cellulose-based immobilized polysaccharide as a chiral stationary phase
    Dhekale, Nitin H.
    Gunjal, Dattatray B.
    Gore, Anil H.
    Komaravolu, Yagnakirankumar
    Bindu, K. Hima
    Kolekar, Govind B.
    CHIRALITY, 2018, 30 (08) : 982 - 987
  • [5] Preparation of a new immobilized cellulose-based chiral stationary phase and its enantioseparation behaviors
    Tu Hongsheng
    Fan Jun
    Tan Yi
    Lin Chun
    Hua Jiangying
    Zhang Weiguang
    CHINESE JOURNAL OF CHROMATOGRAPHY, 2014, 32 (05) : 452 - 457
  • [6] Effect of solvents on the chiral recognition mechanisms of immobilized cellulose-based chiral stationary phase
    Tsui, Hung-Wei
    Ye, Pei-Wen
    Huang, Si-Xian
    JOURNAL OF CHROMATOGRAPHY A, 2021, 1637
  • [7] Chiral separations of pesticide enantiomers by high-performance liquid chromatography using cellulose triphenylcarbamate chiral stationary phase
    Wang, Peng
    Jiang, Shuren
    Liu, Donghui
    Shan, Weili
    Zhang, Hongjun
    Zhou, Zhiqiang
    JOURNAL OF CHROMATOGRAPHIC SCIENCE, 2006, 44 (10) : 602 - 606
  • [8] Preparation and Enantioseparation Characteristics of a Novel β-Cyclodextrin Derivative Chiral Stationary Phase in High-Performance Liquid Chromatography
    Zhou, Jie
    Pei, Wenjuan
    Zheng, Xuxia
    Zhao, Suzhen
    Zhang, Zhenzhong
    JOURNAL OF CHROMATOGRAPHIC SCIENCE, 2015, 53 (05) : 676 - 679
  • [9] Novel chiral ionic liquids stationary phases for the enantiomer separation of chiral acid by high-performance liquid chromatography
    He, Shanshan
    He, Yunchao
    Cheng, Lingping
    Wu, Yaling
    Ke, Yanxiong
    CHIRALITY, 2018, 30 (05) : 670 - 679
  • [10] Green high-performance liquid chromatography enantioseparation of lansoprazole using a cellulose-based chiral stationary phase under ethanol/water mode
    Ferretti, Rosella
    Zanitti, Leo
    Casulli, Adriano
    Cirilli, Roberto
    JOURNAL OF SEPARATION SCIENCE, 2016, 39 (08) : 1418 - 1424
12345