The fuss about Mus81

被引:76
作者
Haber, JE [1 ]
Heyer, WD
机构
[1] Brandeis Univ, Rosenstiel Basic Med Sci Res Ctr, Waltham, MA 02254 USA
[2] Brandeis Univ, Dept Biol, Waltham, MA 02254 USA
[3] Univ Calif Davis, Ctr Genet & Dev, Microbiol Sect, Davis, CA 95616 USA
[4] Univ Calif Davis, Ctr Genet & Dev, Sect Mol & Cellular Biol, Davis, CA 95616 USA
关键词
D O I
10.1016/S0092-8674(01)00593-1
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Endonucleolytic cleavage of Holliday junctions is important in recombination and replication. Mus81 proteins in yeasts and humans appear to have many,,but not all, of the expected properties of eukaryotic Holliday junction resolvases, with intriguing connections to DNA replication checkpoints.
引用
收藏
页码:551 / 554
页数:4
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