Intralesional chemotherapy for head and neck carcinoma: A review of the literature

被引：3
作者：
Barasch, A
Epstein, JB
Foong, WC
Clayman, L
机构：
[1] Univ Detroit, Mercy Sch Dent, Dept Diagnost Sci, Detroit, MI 48219 USA
[2] Univ Illinois, Coll Dent, Dept Oral Med & Diagnost Sci, Chicago, IL USA
[3] Univ Detroit, Chicago Canc Ctr, Coll Med, Interdisciplinary Program Oral Canc, Detroit, MI 48219 USA
[4] Univ Detroit, Mercy Sch Dent, Dept Biomed Sci, Detroit, MI 48219 USA
[5] Univ Detroit, Mercy Sch Dent, Dept Oral Surg, Detroit, MI 48219 USA
来源：
ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTOLOGY | 2004年 / 97卷 / 03期
关键词：
D O I：
10.1016/j.tripleo.2003.12.016
中图分类号：
R78 [口腔科学];
学科分类号：
1003 ;
摘要：
In the last decade chemotherapy has gained widespread acceptance in the treatment of oral and pharyngeal cancer. Current standard treatment for advanced lesions consists of concomitant radiation and chemotherapy. This approach has provided marginal improvement of prognosis for Stage III-IV disease. Recent studies have explored the idea that locally delivered cytotoxic drugs could further improve prognosis in this patient population. We review this literature with the objective of popularizing these data and suggesting future directions for treatment and clinical research for head and neck cancer.
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收藏
页码：307 / 311
页数：5
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