The etiology of autoimmune diseases: the case of myasthenia gravis

被引：11
作者：
Bach, Jean-Francois [1 ]
机构：
[1] Acad Sci, F-75006 Paris, France
来源：
MYASTHENIA GRAVIS AND RELATED DISORDERS I | 2012年 / 1274卷
关键词：
myasthenia gravis; autoimmunity; genetics; epigenetics; MULTIPLE-SCLEROSIS BRAIN; EPSTEIN-BARR-VIRUS; MOLECULAR MIMICRY; GUT MICROBIOTA; SUSCEPTIBILITY; INFECTION;
D O I：
10.1111/j.1749-6632.2012.06774.x
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Autoimmune diseases comprise a wide variety of disorders, from those that are acute and spontaneously regressive to chronic diseases. Their occurrence is the sign of a loss of tolerance to self-antigens. With few exceptions, the etiology of autoimmune diseases has not been clearly established. In all cases, it is complex, involving genetic, epigenetic, and environmental factors. In this article I will attempt to analyze the various factors that have a triggering or protecting role, with particular reference to myasthenia gravis.
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收藏
页码：33 / 39
页数：7
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