Information for decision-making and stimulus identification is multiplexed in sensory cortex

被引：66

作者：

Gire, David H. ^{[1
,2
]}

Whitesell, Jennifer D. ^{[2
,3
]}

Doucette, Wilder ^{[1
,2
]}

Restrepo, Diego ^{[1
,2
]}

机构：

[1] Univ Colorado, Sch Med, Dept Cell & Dev Biol, Aurora, CO USA

[2] Univ Colorado, Sch Med, Neurosci Program, Aurora, CO USA

[3] Univ Colorado, Sch Med, Dept Physiol & Biophys, Aurora, CO USA

来源：

NATURE NEUROSCIENCE | 2013年 / 16卷 / 08期

基金：

美国国家卫生研究院;

关键词：

FALSE DISCOVERY RATE; OLFACTORY-BULB; ODOR REPRESENTATIONS; PERCEPTION; RESPONSES; PHASE;

D O I：

10.1038/nn.3432

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

In recordings from anterior piriform cortex in awake behaving mice, we found that neuronal firing early in the olfactory pathway simultaneously conveyed fundamentally different information: odor value (is the odor rewarded?) and identity (what is the smell?). Thus, this sensory system performs early multiplexing of information reflecting stimulus-specific characteristics with that used for decision-making.

引用

页码：991 / U25

页数：4

共 22 条

[1]

Benjamini Y, 2001, ANN STAT, V29, P1165

[2] Quantitative trait loci analysis using the false discovery rate [J].

Benjamini, Y ;

Yekutieli, D .

GENETICS, 2005, 171 (02) :783-789

[3] Neuronal filtering of multiplexed odour representations [J].

Blumhagen, Francisca ;

Zhu, Peixin ;

Shum, Jennifer ;

Schaerer, Yan-Ping Zhang ;

Yaksi, Emre ;

Deisseroth, Karl ;

Friedrich, Rainer W. .

NATURE, 2011, 479 (7374) :493-U215

[4] RESPIRATORY-PHASE-RELATED CODING OF OLFACTORY INFORMATION IN THE OLFACTORY-BULB OF AWAKE FREELY-BREATHING RABBITS [J].

CHAPUT, MA .

PHYSIOLOGY & BEHAVIOR, 1986, 36 (02) :319-324

[5] Multiple comparisons: philosophies and illustrations [J].

Curran-Everett, D .

AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, 2000, 279 (01) :R1-R8

[6] Robust Odor Coding via Inhalation-Coupled Transient Activity in the Mammalian Olfactory Bulb [J].

Cury, Kevin M. ;

Uchida, Naoshige .

NEURON, 2010, 68 (03) :570-585

[7] Associative Cortex Features in the First Olfactory Brain Relay Station [J].

Doucette, Wilder ;

Gire, David H. ;

Whitesell, Jennifer ;

Carmean, Vanessa ;

Lucero, Mary T. ;

Restrepo, Diego .

NEURON, 2011, 69 (06) :1176-1187

[8] Profound Context-Dependent Plasticity of Mitral Cell Responses in Olfactory Bulb [J].

Doucette, Wilder ;

Restrepo, Diego .

PLOS BIOLOGY, 2008, 6 (10) :2266-2285

[9] Central mechanisms of odour object perception [J].

Gottfried, Jay A. .

NATURE REVIEWS NEUROSCIENCE, 2010, 11 (09) :628-641

[10] Encoding Odorant Identity by Spiking Packets of Rate-Invariant Neurons in Awake Mice [J].

Gschwend, Olivier ;

Beroud, Jonathan ;

Carleton, Alan .

PLOS ONE, 2012, 7 (01)

← 1 2 3 →