Substitution of α-azido ethers with Grignard reagents and its use in combinatorial chemistry

被引：8

作者：

Baruah, M ^{[1
]}

Bols, M ^{[1
]}

机构：

[1] Aarhus Univ, Dept Chem, DK-8000 Aarhus C, Denmark

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 2002年 / 04期

关键词：

D O I：

10.1039/b110428b

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

alpha-Azidobenzyl ethers were reacted with alkyl or arylGrignard reagents in toluene to produce alpha-alkylbenzyl or diarylmethyl ethers in 82-94% yield. alpha-Azidobenzyl ethers were also reacted with multicomponent Grignard reagents to produce libraries of alpha-alkylbenzyl ethers.

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页码：509 / 512

页数：4

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