Clinical validation of the ThyroSeq v3 genomic classifier in thyroid nodules with indeterminate FNA cytology

被引:58
|
作者
Nikiforov, Yuri E. [1 ]
Baloch, Zubair W. [2 ]
机构
[1] Univ Pittsburgh, Dept Pathol, 3477 Euler Way,Rm 8031, Pittsburgh, PA 15213 USA
[2] Hosp Univ Penn, Perelman Sch Med, Dept Pathol & Lab Med, 3400 Spruce St, Philadelphia, PA 19104 USA
基金
美国国家卫生研究院;
关键词
benign call rate; indeterminate FNA; next generation sequencing; thyroid nodule; ThyroSeq; FINE-NEEDLE-ASPIRATION; UNDETERMINED SIGNIFICANCE/FOLLICULAR LESION; CANCER-DIAGNOSIS; BETHESDA SYSTEM; HIGH PREVALENCE; MANAGEMENT; MUTATIONS; CARCINOMA; NEOPLASM; CYTOPATHOLOGY;
D O I
10.1002/cncy.22112
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:225 / 230
页数:6
相关论文
共 50 条
  • [41] Do Ultrasound Patterns and Clinical Parameters Inform the Probability of Thyroid Cancer Predicted by Molecular Testing in Nodules with Indeterminate Cytology?
    Figge, James J.
    Gooding, William E.
    Steward, David L.
    Yip, Linwah
    Sippel, Rebecca S.
    Yang, Samantha Peiling
    Scheri, Randall P.
    Sipos, Jennifer A.
    Mandel, Susan J.
    Mayson, Sarah E.
    Burman, Kenneth D.
    Folek, Jessica M.
    Haugen, Bryan R.
    Sosa, Julie A.
    Parameswaran, Rajeev
    Tan, Wee Boon
    Nikiforov, Yuri E.
    Carty, Sally E.
    THYROID, 2021, 31 (11) : 1673 - 1682
  • [42] European experience with the Afirma Gene Expression Classifier for indeterminate thyroid nodules: A clinical utility study in the Netherlands
    Loncar, Ivona
    van Velsen, Evert F. S.
    Massolt, Elske T.
    van Kemenade, Folkert J.
    van Engen-van Grunsven, Adriana C. H.
    van Hemel, Bettien M.
    van Nederveen, Francien H.
    Netea-Maier, Romana
    Links, Thera P.
    Peeters, Robin P.
    van Ginhoven, Tessa M.
    HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 2023, 45 (09): : 2227 - 2236
  • [43] Use of the Afirma Xpression Atlas for cytologically indeterminate, Afirma Genomic Sequencing Classifier suspicious thyroid nodules: Clinicopathologic analysis with postoperative molecular testing
    Munoz-Zuluaga, Carlos A.
    Heymann, Jonas J.
    Solomon, James P.
    Patel, Ami
    Siddiqui, Momin T.
    Scognamiglio, Theresa
    Gokozan, Hamza N.
    AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 2024, 161 (05) : 463 - 468
  • [44] Clinical utility of a microRNA classifier in cytologically indeterminate thyroid nodules with RAS mutations: A multi-institutional study
    Tumati, Abhinay
    Egan, Caitlin E.
    Lee-Saxton, Yeon J.
    Marshall, Teagan E.
    Lee, Joyce
    Jain, Kavita
    Heymann, Jonas J.
    Gokozan, Hamza
    Abou Azar, Sara
    Schwarz, Jason
    Keutgen, Xavier M.
    Laird, Amanda M.
    Beninato, Toni
    Zarnegar, Rasa
    Fahey II, Thomas J.
    Finnerty, Brendan M.
    SURGERY, 2024, 175 (01) : 234 - 240
  • [45] Evaluation of 167 Gene Expression Classifier (GEC) and ThyroSeq v2 Diagnostic Accuracy in the Preoperative Assessment of Indeterminate Thyroid Nodules: Bivariate/HROC Meta-analysis (vol 30, pg 8, 2019)
    Borowczyk, Martyna
    Szczepanek-Parulska, Ewelina
    Olejarz, Michal
    Wieckowska, Barbara
    Verburg, Frederik A.
    Debicki, Szymon
    Budny, Bartlomiej
    Janicka-Jedynska, Malgorzata
    Ziemnicka, Katarzyna
    Ruchala, Marek
    ENDOCRINE PATHOLOGY, 2019, 30 (01) : 16 - 16
  • [46] Thyroid nodules with indeterminate cytology: association between nodule size, histopathological characteristics and clinical outcome in differentiated thyroid carcinomas - a multicenter retrospective cohort study on 761 patients
    Cozzani, Federico
    Bettini, Dario
    Rossini, Matteo
    Bonati, Elena
    Nuzzo, Simona
    Loderer, Tommaso
    Pedrazzi, Giuseppe
    Zaccaroni, Alberto
    Del Rio, Paolo
    UPDATES IN SURGERY, 2021, 73 (05) : 1923 - 1930
  • [47] A Pilot Study of Galectin-3, HBME-1, and p27 Triple Immunostaining Pattern for Diagnosis of Indeterminate Thyroid Nodules in Cytology With Correlation to Histology
    Zhang, Lei
    Krausz, Thomas
    DeMay, Richard M.
    APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY, 2015, 23 (07) : 481 - 490
  • [48] Does Addition of BRAF V600E Mutation Testing Modify Sensitivity or Specificity of the Afirma Gene Expression Classifier in Cytologically Indeterminate Thyroid Nodules?
    Kloos, Richard T.
    Reynolds, Jessica D.
    Walsh, P. Sean
    Wilde, Jonathan I.
    Tom, Edward Y.
    Pagan, Moraima
    Barbacioru, Catalin
    Chudova, Darya I.
    Wong, Mei
    Friedman, Lyssa
    LiVolsi, Virginia A.
    Rosai, Juan
    Lanman, Richard B.
    Kennedy, Giulia C.
    JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2013, 98 (04) : E761 - E768
  • [49] Exploring the atypia of undetermined significance: Malignant ratio, ThyroSeq v3 positive call rate, molecular-derived risk of malignancy, and risk of malignancy as possible quality metric tools in thyroid cytology
    Torres, Jaylou M. Velez
    Curnow, Porshya M.
    Tjendra, Youley
    Jorda, Merce
    Fernandez, Carmen Gomez
    Buitrago, Monica Garcia
    Zuo, Yiqin
    Cordero, Roberto Ruiz
    CANCER CYTOPATHOLOGY, 2024, 132 (08) : 491 - 498
  • [50] Indeterminate for malignancy' (Tir3/Thy3 in the Italian and British systems for classification) thyroid fine needle aspiration (FNA) cytology reporting: morphological criteria and clinical impact
    Pagni, F.
    Prada, M.
    Goffredo, P.
    Isimbaldi, G.
    Crippa, S.
    Di Bella, C.
    Leone, B. E.
    CYTOPATHOLOGY, 2014, 25 (03) : 170 - 176