Clinical validation of the ThyroSeq v3 genomic classifier in thyroid nodules with indeterminate FNA cytology

被引:58
|
作者
Nikiforov, Yuri E. [1 ]
Baloch, Zubair W. [2 ]
机构
[1] Univ Pittsburgh, Dept Pathol, 3477 Euler Way,Rm 8031, Pittsburgh, PA 15213 USA
[2] Hosp Univ Penn, Perelman Sch Med, Dept Pathol & Lab Med, 3400 Spruce St, Philadelphia, PA 19104 USA
基金
美国国家卫生研究院;
关键词
benign call rate; indeterminate FNA; next generation sequencing; thyroid nodule; ThyroSeq; FINE-NEEDLE-ASPIRATION; UNDETERMINED SIGNIFICANCE/FOLLICULAR LESION; CANCER-DIAGNOSIS; BETHESDA SYSTEM; HIGH PREVALENCE; MANAGEMENT; MUTATIONS; CARCINOMA; NEOPLASM; CYTOPATHOLOGY;
D O I
10.1002/cncy.22112
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:225 / 230
页数:6
相关论文
共 50 条
  • [21] Thyroseq v3, Afirma GSC, and microRNA Panels Versus Previous Molecular Tests in the Preoperative Diagnosis of Indeterminate Thyroid Nodules: A Systematic Review and Meta-Analysis
    Silaghi, Cristina Alina
    Lozovanu, Vera
    Georgescu, Carmen Emanuela
    Georgescu, Raluca Diana
    Susman, Sergiu
    Nasui, Bogdana Adriana
    Dobrean, Anca
    Silaghi, Horatiu
    FRONTIERS IN ENDOCRINOLOGY, 2021, 12
  • [22] Probability of malignancy and molecular alterations as determined by ThyroSeq v3 genomic classifier in Bethesda Category IV
    Tjendra, Youley
    Kerr, Darcy A.
    Zuo, Yiqin
    Menendez, Silvia Gra
    Jorda, Merce
    Gomez-Fernandez, Carmen
    Torres, Jaylou M. Velez M.
    CANCER CYTOPATHOLOGY, 2023, 131 (09) : 586 - 595
  • [23] Performance of a multigene genomic classifier and clinical parameters in predicting malignancy in a Southeast Asian cohort of patients with cytologically indeterminate thyroid nodules
    Yang, Samantha Peiling
    Nga, Min En
    Bundele, Manish Mahadeorao
    Chiosea, Simion I.
    Tan, Sze Hwa
    Lum, Jeffrey H. Y.
    Parameswaran, Rajeev
    Lim, Ming Yann
    Li, Hao
    Cheah, Wei Keat
    Sek, Kathleen Su-Yen
    Tan, Andre Teck Huat
    Loh, Thomas Kwok Seng
    Ngiam, Kee Yuan
    Tan, Wee Boon
    Huang, Xinyong
    Ho, Thomas Wai Thong
    Lim, Keng Hua
    Lim, Chwee Ming
    Singaporewalla, Reyaz M.
    Rao, Anil Dinkar
    Rao, Nandini C. L.
    Chua, Dennis Yu Kim
    Chin, David Chao-Wu
    Wald, Abigail I.
    Livolsi, Virginia A.
    Nikiforov, Yuri E.
    Tai, E. Shyong
    CANCER CYTOPATHOLOGY, 2024, 132 (05) : 309 - 319
  • [24] Molecular Profiling of 50 734 Bethesda III-VI Thyroid Nodules by ThyroSeq v3: Implications for Personalized Management
    Chiosea, Simion
    Hodak, Steven P.
    Yip, Linwah
    Abraham, Devaprabu
    Baldwin, Chelsey
    Baloch, Zubair
    Gulec, Seza A.
    Hannoush, Zeina C.
    Haugen, Bryan R.
    Joseph, Lija
    Kargi, Atil Y.
    Khanafshar, Elham
    Livhits, Masha J.
    McIver, Bryan
    Patel, Kepal
    Patel, Snehal G.
    Randolph, Gregory W.
    Shaha, Ashok R.
    Sharma, Jyotirmay
    Stathatos, Nikolaos
    van Zante, Annemieke
    Carty, Sally E.
    Nikiforov, Yuri E.
    Nikiforova, Marina N.
    JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2023, 108 (11) : 2999 - 3008
  • [25] Shear wave elastography and Afirma™ gene expression classifier in thyroid nodules with indeterminate cytology: a comparison study
    Azizi, Ghobad
    Keller, James M.
    Mayo, Michelle L.
    Piper, Kele
    Puett, David
    Earp, Karly M.
    Malchoff, Carl D.
    ENDOCRINE, 2018, 59 (03) : 573 - 584
  • [26] Thyroid FNA cytology in Asian practiceActive surveillance for indeterminate thyroid nodules reduces overtreatment of thyroid carcinomas
    Kakudo, K.
    Higuchi, M.
    Hirokawa, M.
    Satoh, S.
    Jung, C. K.
    Bychkov, A.
    CYTOPATHOLOGY, 2017, 28 (06) : 455 - 466
  • [27] Risk of malignancy in thyroid nodules with indeterminate (THY3f) cytology
    de Jong, Mc
    McNamara, J.
    Winter, L.
    Roskell, D.
    Khan, S.
    Mihai, R.
    ANNALS OF THE ROYAL COLLEGE OF SURGEONS OF ENGLAND, 2022, 104 (09) : 703 - 709
  • [28] Indeterminate thyroid nodules (TIR3A/TIR3B) according to the new Italian reporting system for thyroid cytology: A cytomorphological study
    Rullo, Emma
    Minelli, Giada
    Bosco, Daniela
    Nardi, Francesco
    Grani, Giorgio
    Durante, Cosimo
    Ascoli, Valeria
    CYTOPATHOLOGY, 2019, 30 (05) : 475 - 484
  • [29] The Effect of Implementing Gene Expression Classifier on Outcomes of Thyroid Nodules with Indeterminate Cytology
    Jithma Prasad Abeykoon
    Luke Mueller
    Frank Dong
    Ashish V. Chintakuntlawar
    Jonas Paludo
    Rami Mortada
    Hormones and Cancer, 2016, 7 : 272 - 278
  • [30] Bethesda III and IV Thyroid Nodules Managed Nonoperatively After Molecular Testing With Afirma GSC or Thyroseq v3
    Kim, Na Eun
    Raghunathan, Rajam S.
    Hughes, Elena G.
    Longstaff, Xochitl R.
    Tseng, Chi-Hong
    Li, Shanpeng
    Cheung, Dianne S.
    Gofnung, Yaroslav A.
    Famini, Pouyan
    Wu, James X.
    Yeh, Michael W.
    Livhits, Masha J.
    JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2023, 108 (09) : E698 - E703