The Effectiveness of Repetitive Transcranial Magnetic Stimulation for Poststroke Apathy Is Associated with Improved Interhemispheric Functional Connectivity

被引：9

作者：

Mitaki, Shingo ^{[1
]}

Onoda, Keiichi ^{[1
]}

Abe, Satoshi ^{[1
]}

Oguro, Hiroaki ^{[1
]}

Yamaguchi, Shuhei ^{[1
]}

机构：

[1] Shimane Univ, Dept Neurol, Fac Med, 89-1 Enya Cho, Izumo, Shimane 6938501, Japan

来源：

JOURNAL OF STROKE & CEREBROVASCULAR DISEASES | 2016年 / 25卷 / 12期

基金：

日本学术振兴会;

关键词：

Poststroke apathy; repetitive transcranial magnetic stimulation; corpus callosum; resting-state functional magnetic resonance imaging; interhemispheric functional connectivity; BRAIN;

D O I：

10.1016/j.jstrokecerebrovasdis.2016.05.014

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Poststroke apathy is relatively common and has negative effects on the functional recovery of the patient; however, few reports have demonstrated the existence of effective treatments for poststroke apathy. Here, we describe a case of poststroke apathy that was successfully treated with repetitive transcranial magnetic stimulation (rTMS). Using resting-state functional magnetic resonance imaging, we detected improved interhemispheric functional connectivity that was correlated with the patient's recovery from poststroke apathy. Our case suggests that rTMS can improve the transfer of information through the corpus callosum, which is crucial for helping patients recover from poststroke apathy. (C) 2016 National Stroke Association. Published by Elsevier Inc. All rights reserved.

引用

页码：E219 / E221

页数：3

共 8 条

[1] Transcallosal sensorimotor fiber tract structure-function relationships [J].

Fling, Brett W. ;

Benson, Bryan L. ;

Seidler, Rachael D. .

HUMAN BRAIN MAPPING, 2013, 34 (02) :384-395

[2] Cerebral specialization and interhemispheric communication - Does the corpus callosum enable the human condition? [J].

Gazzaniga, MS .

BRAIN, 2000, 123 :1293-1326

[3] Neural correlates of apathy revealed by lesion mapping in participants with traumatic brain injuries [J].

Knutson, Kristine M. ;

Dal Monte, Olga ;

Raymont, Vanessa ;

Wassermann, Eric M. ;

Krueger, Frank ;

Grafman, Jordan .

HUMAN BRAIN MAPPING, 2014, 35 (03) :943-953

[4]

Okada K., 1998, Jpn. J. Stroke, V20, P318, DOI [10.3995/jstroke.20.318, DOI 10.3995/JSTROKE.20.318]

[5] Modulating Intrinsic Connectivity: Adjacent Subregions within Supplementary Motor Cortex, Dorsolateral Prefrontal Cortex, and Parietal Cortex Connect to Separate Functional Networks during Task and Also Connect during Rest [J].

Roth, Jennifer K. ;

Johnson, Marcia K. ;

Tokoglu, Fuyuze ;

Murphy, Isabella ;

Constable, R. Todd .

PLOS ONE, 2014, 9 (03)

[6] Functional Coactivation Map of the Human Brain [J].

Toro, Roberto ;

Fox, Peter T. ;

Paus, Tomas .

CEREBRAL CORTEX, 2008, 18 (11) :2553-2559

[7] Deficiency of brain structural sub-network underlying post-ischaemic stroke apathy [J].

Yang, S. ;

Hua, P. ;

Shang, X. ;

Cui, Z. ;

Zhong, S. ;

Gong, G. ;

Humphreys, G. William .

EUROPEAN JOURNAL OF NEUROLOGY, 2015, 22 (02) :341-347

[8] Brain resting-state functional MRI connectivity: Morphological foundation and plasticity [J].

Zhou, Iris Y. ;

Liang, Yu-Xiang ;

Chan, Russell W. ;

Gao, Patrick P. ;

Cheng, Joe S. ;

Hu, Yong ;

So, Kwok-Fai ;

Wu, Ed X. .

NEUROIMAGE, 2014, 84 :1-10

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