A new detached-eddy simulation procedure, MBFLO, is described for the simulation of turbulent flow over/within arbitrary geometry. This new procedure represents the first step toward developing a turbulent technique that reduces the reliance on traditional turbulence modeling by directly solving for the larger-scale turbulence effects in regions where the computational grid is sufficient to resolve those scales. A goal of this effort was to develop a detached-eddy simulation procedure for which the time-averaged solution can replace current steady simulation results for design. Because detached-eddy simulation requires the solution of the unsteady Navier-Stokes equations on computational grids that are typically an order in magnitude more dense than their Reynolds-averaged counterparts, special care was taken to make this new procedure computationally efficient. This paper describes the data structure, parallelization, and automation techniques used to produce time-averaged detached-eddy simulation predictions. Results for the turbulent How through a turbine and compressor cascade at design and offdesign conditions, respectively, are shown to illustrate the technique.