Neuroimaging Auditory Hallucinations in Schizophrenia: From Neuroanatomy to Neurochemistry and Beyond

被引：183

作者：

Allen, Paul ^{[1
]}

Modinos, Gemma ^{[1
]}

Hubl, Daniela ^{[2
]}

Shields, Gregory ^{[3
]}

Cachia, Arnaud ^{[4
,5
]}

Jardri, Renaud ^{[6
]}

Thomas, Pierre ^{[6
]}

Woodward, Todd ^{[7
]}

Shotbolt, Paul ^{[3
]}

Plaze, Marion ^{[4
,8
]}

Hoffman, Ralph ^{[9
]}

机构：

[1] Kings Coll London, Dept Psychosis Studies, Inst Psychiat, London SE5 8AF, England

[2] Univ Hosp Psychiat, Bern, Switzerland

[3] Kings Coll London, Dept Psychol Med, Inst Psychiat, London SE5 8AF, England

[4] Sorbonne Univ Paris Descartes, Ctr Psychiat & Neurosci, Ctr Hosp St Anne, INSERM,UMR 894, Paris, France

[5] Sorbonne Univ Paris Descartes, CNRS, Grp Imagerie Neurofonct Dev, UMR 6232, Paris, France

[6] Lille N France Univ, Psychiat Dept, Univ Med Ctr, Lille, France

[7] BC Mental Hlth & Addict Res Inst, Dept Psychiat, Vancouver, BC, Canada

[8] Univ Paris 05, Serv Hosp Univ, Paris, France

[9] Yale Univ, Sch Med, Dept Psychiat, New Haven, CT USA

来源：

SCHIZOPHRENIA BULLETIN | 2012年 / 38卷 / 04期

关键词：

hallucinations; neuroimaging; MRI; PET; DTI; MRS; VERBAL HALLUCINATIONS; ABNORMALITIES; BRAIN; CONNECTIVITY; REALITY; GYRUS; ACTIVATION; PATHWAYS; THALAMUS; VOICES;

D O I：

10.1093/schbul/sbs066

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Despite more than 2 decades of neuroimaging investigations, there is currently insufficient evidence to fully understand the neurobiological substrate of auditory hallucinations (AH). However, some progress has been made with imaging studies in patients with AH consistently reporting altered structure and function in speech and language, sensory, and nonsensory regions. This report provides an update of neuroimaging studies of AH with a particular emphasis on more recent anatomical, physiological, and neurochemical imaging studies. Specifically, we provide (1) a review of findings in schizophrenia and nonschizophrenia voice hearers, (2) a discussion regarding key issues that have interfered with progress, and (3) practical recommendations for future studies.

引用

页码：695 / 703

页数：9

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