Convenient One-Pot Synthesis of 2,4,5-Triaryl-1H-imidazoles from Arylaldehydes, Benzyl Alcohols, or Benzyl Halides with HMDS in the Presence of Molecular Iodine

被引：10

作者：

Veisi, Hojat ^{[1
]}

Khazaei, Ardashir ^{[2
]}

Heshmati, Leila ^{[1
]}

Hemmati, Saba ^{[3
]}

机构：

[1] Payame Noor Univ, Dept Chem, Tehran 193954697, Iran

[2] Bu Ali Sina Univ, Fac Chem, Hamadan, Iran

[3] Islamic Azad Univ, Kermanshah Branch, Kermanshah, Iran

来源：

BULLETIN OF THE KOREAN CHEMICAL SOCIETY | 2012年 / 33卷 / 04期

关键词：

2,4,5-Triaryl-1H-imidazole; Hexamethyldisilazane; Iodine; Aldehydes; SOLVENT-FREE SYNTHESIS; TETRASUBSTITUTED IMIDAZOLES; EFFICIENT SYNTHESIS; HEXAMETHYLDISILAZANE HMDS; SUBSTITUTED IMIDAZOLES; HIGHLY EFFICIENT; ALDEHYDES; CATALYST; ACID; TRIMETHYLSILYLATION;

D O I：

10.5012/bkcs.2012.33.4.1231

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A one-pot efficient procedure for the synthesis of 2,4,5-triaryl-1H-imidazole derivatives in good to excellent yields by reaction between hexamethyldisilazane and arylaldehydes, benzyl alcohols, benzyl halides in the presence of molecular iodine has been developed. The remarkable advantages of this method are the simple workup procedure, high yields of products, and the availability of reagents.

引用

页码：1231 / 1234

页数：4

共 56 条

[41] Sodium bisulfite as an efficient and inexpensive catalyst for the one-pot synthesis of 2,4,5-triaryl-1H-imidazoles from benzil or benzoin and aromatic aldehydes [J].