The diagnosis and management of a case of leishmaniosis in a dog imported to Australia

被引：8
作者：
Best, Matthew P. [1 ]
Ash, Amanda [2 ]
Bergfeld, Jemma [3 ]
Barrett, Janine [4 ]
机构：
[1] Brisbane Vet Specialist Ctr, Albany Creek, Qld 4035, Australia
[2] Murdoch Univ, Sch Vet & Life Sci, Murdoch, WA 6150, Australia
[3] CSIRO Anim Food & Hlth Sci, Australian Anim Hlth Lab, Geelong, Vic 3220, Australia
[4] Biosecur Queensland, Dept Agr Fisheries & Forestry, Brisbane, Qld 4000, Australia
来源：
VETERINARY PARASITOLOGY | 2014年 / 202卷 / 3-4期
关键词：
Australia; Amphotericin B; Dog; Leishmania infantum; PCR; CUTANEOUS LEISHMANIASIS; MEGLUMINE ANTIMONIATE; CANINE LEISHMANIASIS;
D O I：
10.1016/j.vetpar.2014.03.032
中图分类号：
R38 [医学寄生虫学]; Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ; 100103 ;
摘要：
This case study discusses in detail for the first time the diagnosis and management of a case of leishmaniosis in a dog imported to Australia. The dog presented with epistaxis and a non-regenerative anaemia five years after being imported from Europe. Protozoa were identified within macrophages in bone marrow and splenic cytology. A Leishmania indirect fluorescent antibody test was performed and was positive while an Ehrlichia canis antibody test was negative. Polymerase chain reaction of the ITS-1 and ITS-2 regions of skin, lymph node, spleen and bone marrow were all positive for Leishmania infantum. The dog was treated with amphotericin B with a strong clinical response. The importance of thorough diagnostics in non-endemic areas, particularly Australia, is discussed. Treatment with amphotericin B is discussed. Vigilance, disease reporting and response frameworks are recommended for non-endemic areas. (C) 2014 Elsevier B.V. All rights reserved.
引用
收藏
页码：292 / 295
页数：4
相关论文
共 19 条
[1]   Efficacy of Combined Therapy with Liposome-Encapsulated Meglumine Antimoniate and Allopurinol in Treatment of Canine Visceral Leishmaniasis [J].
da Silva, Sydnei M. ;
Amorim, Izabela F. G. ;
Ribeiro, Raul R. ;
Azevedo, Erly G. ;
Demicheli, Cynthia ;
Melo, Maria N. ;
Tafuri, Wagner L. ;
Gontijo, Nelder F. ;
Michalick, Marilene S. M. ;
Frezard, Frederic .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2012, 56 (06) :2858-2867
[2]   Canine leishmaniosis in the Old and New Worlds: unveiled similarities and differences [J].
Dantas-Torres, Filipe ;
Solano-Gallego, Laia ;
Baneth, Gad ;
Ribeiro, Vitor Marcio ;
de Paiva-Cavalcanti, Milena ;
Otranto, Domenico .
TRENDS IN PARASITOLOGY, 2012, 28 (12) :531-538
[3]   New reports of Australian cutaneous leishmaniasis in Northern Australian macropods [J].
Dougall, A. ;
Shilton, C. ;
Choy, J. Low ;
Alexander, B. ;
Walton, S. .
EPIDEMIOLOGY AND INFECTION, 2009, 137 (10) :1516-1520
[4]   Evidence incriminating midges (Diptera: Ceratopogonidae) as potential vectors of Leishmania in Australia [J].
Dougall, Annette M. ;
Alexander, Bruce ;
Holt, Deborah C. ;
Harris, Tegan ;
Sultan, Amal H. ;
Bates, Paul A. ;
Rose, Karrie ;
Walton, Shelley F. .
INTERNATIONAL JOURNAL FOR PARASITOLOGY, 2011, 41 (05) :571-579
[5]   Genetic heterogeneity of ribosomal internal transcribed spacer in clinical samples of Leishmania donovani spotted on filter paper as revealed by single-strand conformation polymorphisms and sequencing [J].
El Tai, NO ;
Osman, OF ;
El Fari, M ;
Presber, W ;
Schönian, G .
TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, 2000, 94 (05) :575-579
[6]   Comparison of serological assays for the diagnosis of canine visceral leishmaniasis in animals presenting different clinical manifestations [J].
Ferreira, Eduardo de Castro ;
de Lana, Marta ;
Carneiro, Mariangela ;
Reis, Alexandre Barbosa ;
Paes, Daniela Vieira ;
da Silva, Eduardo Sergio ;
Schallig, Henk ;
Ferreira Gontijo, Celia Maria .
VETERINARY PARASITOLOGY, 2007, 146 (3-4) :235-241
[7]   Climate Change and Risk of Leishmaniasis in North America: Predictions from Ecological Niche Models of Vector and Reservoir Species [J].
Gonzalez, Camila ;
Wang, Ophelia ;
Strutz, Stavana E. ;
Gonzalez-Salazar, Constantino ;
Sanchez-Cordero, Victor ;
Sarkar, Sahotra .
PLOS NEGLECTED TROPICAL DISEASES, 2010, 4 (01)
[8]   Recent advances in leishmaniosis in pet animals: Epidemiology, diagnostics and anti-vectorial prophylaxis [J].
Gramiccia, M. .
VETERINARY PARASITOLOGY, 2011, 181 (01) :23-30
[9]   Study of efficacy of miltefosine and allopurinol in dogs with leishmaniosis [J].
Manna, Laura ;
Vitale, Fabrizio ;
Reale, Stefano ;
Picillo, Esther ;
Neglia, Gianluca ;
Vescio, Francesco ;
Gravino, Angelo Elio .
VETERINARY JOURNAL, 2009, 182 (03) :441-445
[10]   Validation of a Leishmania infantum ELISA rapid test for serological diagnosis of Leishmania chagasi in dogs [J].
Marcondes, M. ;
Biondo, A. W. ;
Gomes, A. A. D. ;
Silva, A. R. S. ;
Vieira, R. F. C. ;
Camacho, A. A. ;
Quinn, John ;
Chandrashekarg, R. .
VETERINARY PARASITOLOGY, 2011, 175 (1-2) :15-19
12