Replacement of C-Terminal Histidines Uncouples Membrane Insertion and Translocation in Diphtheria Toxin T-Domain

被引：0
|
作者：
Vargas-Uribe, Mauricio [1 ]
Rodnin, Mykola V. [1 ]
Kyrychenko, Alexander [1 ]
Kienker, Paul [2 ]
Sharma, Onkar [3 ]
Collier, R. John [3 ]
Finkelstein, Alan [2 ]
Ladokhin, Alexey S. [1 ]
机构：
[1] KUMC, Kansas City, KS USA
[2] Albert Einstein Coll Med, Bronx, NY 10467 USA
[3] Harvard Univ, Sch Med, Boston, MA USA
来源：
BIOPHYSICAL JOURNAL | 2012年 / 102卷 / 03期
关键词：
D O I：
10.1016/j.bpj.2011.11.1350
中图分类号：
Q6 [生物物理学];
学科分类号：
071011 ;
摘要：
引用
收藏
页码：245A / 245A
页数：1
相关论文
共 50 条
  • [41] MEMBRANE TRANSLOCATION OF DIPHTHERIA TOXIN-A-FRAGMENT - ROLE OF CARBOXY-TERMINAL REGION
    ARIANSEN, S
    AFANASIEV, BN
    MOSKAUG, JO
    STENMARK, H
    MADSHUS, IH
    OLSNES, S
    BIOCHEMISTRY, 1993, 32 (01) : 83 - 90
  • [42] Identifying transmembrane states and defining the membrane insertion boundaries of hydrophobic helices in membrane-inserted diphtheria toxin T domain
    Kachel, K
    Ren, JH
    Collier, RJ
    London, E
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (36) : 22950 - 22956
  • [43] The diphtheria toxin channel-forming T-domain translocates its own NH2-terminal region and the catalytic domain across planar phospholipid bilayers
    Finkelstein, A
    Oh, KJ
    Senzel, L
    Gordon, M
    Blaustein, RO
    Collier, RJ
    INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY, 2000, 290 (4-5) : 435 - 440
  • [44] Topography of the C-terminal domain of the pore-forming toxin, perfringolysin O, on the membrane surface
    Ramachandran, R
    Heuck, AP
    Tweten, RK
    Johnson, AE
    BIOPHYSICAL JOURNAL, 2002, 82 (01) : 530A - 530A
  • [45] Δψ stimulates membrane translocation of the C-terminal part of a signal sequence
    van Dalen, A
    Killian, A
    de Kruijff, B
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (28) : 19913 - 19918
  • [46] Behavior of the N-terminal helices of the diphtheria toxin T domain during the successive steps of membrane interaction
    Montagner, Caroline
    Perier, Aurelie
    Pichard, Sylvain
    Vernier, Gregory
    Menez, Andre
    Gillet, Daniel
    Forge, Vincent
    Chenal, Alexandre
    BIOCHEMISTRY, 2007, 46 (07) : 1878 - 1887
  • [47] Crucial Role of H322 in the Folding of Diphtheria Toxin T-Domain into the Open-Channel State
    Vargas-Uribe, Mauricio
    Rodnin, Mykola V.
    Kienker, Paul
    Finkelstein, Alan
    Ladokhin, Alexey S.
    BIOPHYSICAL JOURNAL, 2014, 106 (02) : 717A - 717A
  • [48] Topography of the entire membrane-inserted diphtheria toxin T domain
    Rosconi, MP
    Wang, J
    Zhao, G
    London, E
    BIOPHYSICAL JOURNAL, 2003, 84 (02) : 58A - 58A
  • [49] Interaction of the diphtheria toxin translocation domain with membranes: role of its N-terminal part
    不详
    EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, 2005, 34 (06): : 791 - 791
  • [50] Solution and membrane-bound chaperone activity of the diphtheria toxin translocation domain towards the catalytic domain
    Chassaing, Anne
    Pichard, Sylvain
    Araye-Guet, Anne
    Barbier, Julien
    Forge, Vincent
    Gillet, Daniel
    FEBS JOURNAL, 2011, 278 (23) : 4516 - 4525
12345