Design and Synthesis of Urazole Derivatives via Ring Closing Metathesis

被引：2

作者：

Kotha, Sambasivarao ^{[1
]}

Singh, Deepshikha ^{[1
]}

Bandi, Vijayalakshmi ^{[1
]}

机构：

[1] Indian Inst Technol, Dept Chem, Mumbai 400076, Maharashtra, India

来源：

CHEMISTRYSELECT | 2022年 / 7卷 / 42期

关键词：

Urazole; Ring-Closing Metathesis; Isomerization; Allylation; Hydrogenation; OLEFIN-METATHESIS; CRYSTAL-STRUCTURES; COMPLEXES; CATALYSTS; N-METHYL-1,2,4-TRIAZOLINE-3,5-DIONE; BIOCONJUGATION; REARRANGEMENT; POLYCYCLICS; STRATEGIES; TYROSINE;

D O I：

10.1002/slct.202203096

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An efficient and short synthetic sequence to highly functionalized urazole derivatives is reported. N-substituted-1,2,4-triazoline-3,5-dione (TAD) is a versatile synthetic reagent. Here, simple reactions such as allylation, ring-closing metathesis and hydrogenation were used successfully to construct the oxygenated urazole derivatives which may have implications in medicinal chemistry and organic synthesis.

引用

页数：6

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