Using thermally printed transparency as photomasks to generate microfluidic structures in PDMS material

被引：8

作者：

Li, CW ^{[1
]}

Yang, J ^{[1
]}

Tzang, CH ^{[1
]}

Zhao, JL ^{[1
]}

Yang, MS ^{[1
]}

机构：

[1] Chinese Acad Sci, Inst Microsyst & Informat Technol, Biochip Res Lab, Shanghai 200050, Peoples R China

来源：

SENSORS AND ACTUATORS A-PHYSICAL | 2006年 / 126卷 / 02期

基金：

中国国家自然科学基金;

关键词：

microfluidics; multi-height structure; PDMS; cell immobilization;

D O I：

10.1016/j.sna.2005.10.046

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

A simple fabrication method for poly(dimethylsiloxane) (PDMS) microfluidic device with minimal specialized equipment and facilities was described. Thermal color-printed transparency was used as photomask that utilizing patterns of different light opacity to generate multi-height microscale structures. The method offers rapid prototyping (3 h from concept to device) and high throughput production (multiple devices on 8 in. x 12 in. PCB board) capability while allows the customisation of feature depth by controlling etching time of PCB-based master. Leak-proof channel manifold with similar to 200 mu m intervals could be obtained, and multi-height structures provided added functions for the manipulation of liquid and particles in PDMS microfluidic devices. The liquid flow in the channels has the basic laminar flow characteristics and the multi-height structure can be used to trap particles such as biological cells. (C) 2005 Elsevier B.V. All rights reserved.

引用

页码：463 / 468

页数：6

共 16 条

[1] Fabrication of topologically complex three-dimensional microfluidic systems in PDMS by rapid prototyping [J].