Acute angioedema: recognition and management in the emergency department

被引:30
|
作者
Jaiganesh, Thiagarajan [1 ]
Wiese, Martin [3 ]
Hollingsworth, John [4 ]
Hughan, Chris [2 ]
Kamara, Mohamed [5 ]
Wood, Philip [6 ]
Bethune, Claire [7 ]
机构
[1] St George Hosp, Emergency Dept, London SW17 0QT, England
[2] Primary Immunodeficiency Assoc, London, England
[3] Leicester Royal Infirm, Emergency Dept, Leicester, Leics, England
[4] Aintree Univ Hosp NHS Fdn Trust, Emergency Dept, Aintree, Scotland
[5] Fairfield Hosp, Dept Emergency Med, Bury, England
[6] St James Hosp, Dept Clin Immunol, Leeds LS9 7TF, W Yorkshire, England
[7] Plymouth Hosp NHS Trust, Dept Immunol, Plymouth, Devon, England
关键词
angioedema; bradykinin; emergency; swelling; urticaria; HEREDITARY ANGIOEDEMA; CHRONIC URTICARIA; INHIBITOR DEFICIENCY; RECEPTOR ANTAGONIST; EDEMA; ANAPHYLAXIS; BRADYKININ; ATTACKS; GUIDELINES; C1-INHIBITOR;
D O I
10.1097/MEJ.0b013e328356f76e
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Angioedema is characterized by localized swelling of subcutaneous tissues or mucosa of the upper respiratory or gastrointestinal tract. Laryngeal involvement may threaten airway patency and can be fatal if not addressed promptly. There are several distinct subtypes of angioedema, caused by different pathological processes involving a range of proinflammatory mediators. In the emergency department, it is essential not only that acute angioedema is identified as quickly as possible but also that the likely working diagnosis is established so that the most effective treatment may be administered to resolve potentially life-threatening swelling. In this paper, we present an overview of the various types of angioedema, and offer a practical diagnostic and therapeutic approach to their management. European Journal of Emergency Medicine 20: 10-17 (C) 2013 Wolters Kluwer Health vertical bar Lippincott Williams & Wilkins. European Journal of Emergency Medicine 2013, 20: 10-17
引用
收藏
页码:10 / 17
页数:8
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