Dual inhibition of the complement factor C5 and leukotriene B4by the bifunctional soft tick-derived lipocalin Coversin synergizes in suppressing disease in a murine model of bullous pemphigoid-like epidermolysis bullosa acquisita

被引:0
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作者
Sezin, T. [1 ]
Murthy, S. [1 ]
Attah, C. [1 ]
Seutter, M. [1 ]
Zillikens, D. [1 ]
Nunn, M. A. [2 ]
Sadik, C. D. [1 ]
机构
[1] Univ Lubeck, Dept Dermatol, Lubeck, Germany
[2] Akari Therapeut, London, England
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中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
049
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页码:S9 / S9
页数:1
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  • [1] The Ornithodoros moubata soft-tick-derived lipocalin Coversin abrogates skin inflammation in a murine model of pemphigoid diseases by sequestering complement factor C5 and leukotriene B4
    Sezin, T.
    Murthy, S.
    Halim, F.
    Attah, C.
    Seutter, M.
    Holtsche, M.
    Hammers, C. M.
    Schmidt, E.
    Mousavi, S.
    Zillikens, D.
    Nunn, M.
    Sadik, C. D.
    EXPERIMENTAL DERMATOLOGY, 2019, 28 (03) : E61 - E62