Post-PCI acute heart failure is an independent predictor of long-term mortality in patients with chronic kidney disease

被引:2
作者
Guo, Zhaodong [1 ]
Liu, Jin [1 ]
Sun, Guoli [2 ]
Song, Feier [3 ,4 ]
Lei, Li [5 ]
He, Yibo [1 ]
Liu, Bowen [2 ]
Chen, Shiqun [1 ]
Liu, Yong [1 ]
Chen, Jiyan [1 ]
机构
[1] Guangdong Acad Med Sci, Guangdong Cardiovasc Inst, Guangdong Prov Peoples Hosp, Dept Cardiol,Guangdong Prov Key Lab Coronary Hear, Guangzhou, Peoples R China
[2] South China Univ Technol, Guangdong Prov Peoples Hosp, Sch Med, Dept Cardiol, Guangzhou 510100, Guangdong, Peoples R China
[3] Guangdong Prov Peoples Hosp, Dept Emergency & Crit Care Med, Guangzhou 510080, Guangdong, Peoples R China
[4] Guangdong Acad Med Sci, Guangzhou 510080, Guangdong, Peoples R China
[5] Southern Med Univ, Sch Clin Med 2, Dept Cardiol, Guangzhou 510515, Guangdong, Peoples R China
关键词
Post-percutaneous coronary intervention; Acute heart failure; All-cause long-term mortality; Chronic kidney disease; GUIDELINES; DYSFUNCTION; PREVENTION; MANAGEMENT; DIAGNOSIS; SOCIETY; ESC;
D O I
10.1016/j.ijcard.2020.05.074
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background: This study aimed to clarify the association of post-percutaneous coronary intervention (PCI) acute heart failure (AHF) with all-cause long-term mortality in patients with chronic kidney disease (CKD). Methods: In this prospective, observational study, 610 patients with CKD and coronary artery disease (CAD) undergoing PCI were included in the final analysis. Patientswere divided to the non post-PCI AHF group (n= 557) and the post-PCI AHF group (n= 53). The diagnosis of post-PCI AHF was based on symptoms, prior cardiovascular history, and potential cardiac and noncardiac precipitants. Results: The overall incidence of post-PCI AHF was 53/610 (8.7%). The incidence of all-cause long-term mortality was significantly higher in the post-PCI AHF group than in the non post-PCI AHF group (50.9% vs 23.2%, P<.01). The median follow-up period was 7.3 years (interquartile range: 3.7-8.4). After adjusting for left ventricular ejection fraction <40% at discharge, CKD stage, acute myocardial infarction, age and smoking, post-PCI AHF was the strongest predictor of all-cause long-term mortality (hazard ratio: 8.08; 95% CI: 3.04-21.48; P<.01). Conclusions: In patients with CKD and CAD undergoing PCI, post-PCI AHF is the strongest predictor of all-cause long-term mortality. (C) 2020 Published by Elsevier B.V.
引用
收藏
页码:119 / 123
页数:5
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