ECONOMIC ASPECTS OF HOSPITALY TREATED PNEUMOCOCCAL PNEUMONIA AND THE RESULTS OF PNEUMO 23 VACCINE USE IN SERBIA

被引:1
作者
Adzic, Tatjana [1 ]
Rosic, Ilija [2 ]
Jovanovic, Dragana [1 ]
Medic-Stojanac, Snezana [3 ]
机构
[1] Clin Ctr Serbia, Inst Lung Dis & TB, Belgrade 11000, Serbia
[2] Sanofi Pasteur, Belgrade, Serbia
[3] Inst Publ Hlth, Sremska Mitrovica, Serbia
关键词
pneumonia; pneumococcal vaccine; Streptococcus pneumoniae;
D O I
10.2298/SARH0812625A
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
INTRODUCTION In Serbia, there is a significant number of persons suffering of pneumococcal pneumonia. Persons aged 65 years or older, immunocompromised patients, patients with co-morbidities, such as chronic obstructive lung disease and congestive heart failure, are at the highest risk for developing pneumococcal pneumonia. Most of the patients are treated empirically, although it is often overlooked that Streptococcus pneumoniae can be resistant to the used antibiotics. The treatment costs of such inpatients and outpatients are very high. In Serbia, immunization of persons at risk to develop the diseases caused by Streptococcus pneumoniae is carried out using pneumococcus polysaccharide vaccine according to clinical indications. The exact number of immunized persons and the total number of registered patients are still unknown, but it is certain of being unjustifiably low. OBJECTIVE The goal of the study was to investigate, during a one-year period, the number and basic characteristics of persons hospitably treated for pneumonia, the type of cause of the infection, applied antibiotic medications, duration and costs of hospital treatment at the Institute for Lung Diseases and Tuberculosis of the Clinical Centre of Serbia in Belgrade. METHOD We retrospectively analyzed the medical records of patients with pneumonia treated at the Institute for Lung Diseases and Tuberculosis of the Clinical Centre of Serbia in Belgrade during 2006. RESULTS During the observed one-year period, 290 patients underwent hospital treatment, of whom the cause of the infection was confirmed in 116 (40%). The average duration of hospitalization was 12 days, with treatment cost of 32,031.74 RSD (402.42 EUR) per patient. The treatment cost per patient including general and intensive care was 18,290.01 RSD (229.78 EUR). The distribution cost of Pneumo 23 vaccine in Serbia, without purchase tax, was 746.90 RSD (9.38 EUR). CONCLUSION Pneumococcal pneumonia is a significant medical and economic problem for the healthcare system of Serbia. The use of antipneumococcal vaccination can be useful in decreasing the overall treatment costs related to pneumococcal infection.
引用
收藏
页码:625 / 628
页数:4
相关论文
共 17 条
[1]   Cost-effectiveness of pneumococcal vaccination of older people:: A study in 5 western European countries [J].
Ament, A ;
Baltussen, R ;
Duru, G ;
Rigaud-Bully, C ;
de Graeve, D ;
Örtqvist, Å ;
Jönsson, B ;
Verhaegen, J ;
Gaillat, J ;
Christie, P ;
Cifre, AS ;
Vivas, D ;
Loiseau, C ;
Fedson, DS .
CLINICAL INFECTIOUS DISEASES, 2000, 31 (02) :444-450
[2]  
[Anonymous], 1997, MMWR Recomm Rep, V46, P1
[3]  
Bartlett John G., 2000, Clinical Infectious Diseases, V31, P347, DOI 10.1086/313954
[4]   Pneumococcal vaccines:: an update on current strategies [J].
Bogaert, D ;
Hermans, PWM ;
Adrian, PV ;
Rümke, HC ;
de Groot, R .
VACCINE, 2004, 22 (17-18) :2209-2220
[5]  
Chiou CCC, 2006, CURR OPIN CRIT CARE, V12, P470
[6]   Economic aspects of pneumococcal pneumonia - A review of the literature [J].
De Graeve, D ;
Beutels, P .
PHARMACOECONOMICS, 2004, 22 (11) :719-740
[7]  
FARR M, 1997, NEW ENGL J MED, V336, P243
[8]   Antimicrobial susceptibility and pneumococcal serotypes [J].
Fenoll, A ;
Asensio, G ;
Jado, I ;
Berrón, S ;
Camacho, MT ;
Ortega, M ;
Casal, J .
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2002, 50 :13-19
[9]   Update of practice guidelines for the management of community-acquired pneumonia in immunocompetent adults [J].
Mandell, LA ;
Bartlett, JG ;
Dowell, SF ;
File, TM ;
Musher, DM ;
Whitney, C .
CLINICAL INFECTIOUS DISEASES, 2003, 37 (11) :1405-1432
[10]   The 23-valent pneumococcal polysaccharide vaccine. Part I. Efficacy of PPV in the elderly: A comparison of meta-analyses [J].
Melegaro A. ;
Edmunds W.J. .
European Journal of Epidemiology, 2004, 19 (4) :353-363