Bayesian non-parametric inference for Λ-coalescents: Posterior consistency and a parametric method

被引:3
作者
Koskela, Jere [1 ]
Jenkins, Paul A. [2 ,3 ]
Spano, Dario [2 ]
机构
[1] Tech Univ Berlin, Inst Math, Str 17 Juni 136, D-10623 Berlin, Germany
[2] Univ Warwick, Dept Stat, Coventry CV4 7AL, W Midlands, England
[3] Univ Warwick, Dept Comp Sci, Coventry CV4 7AL, W Midlands, England
基金
英国工程与自然科学研究理事会;
关键词
Dirichlet mixture model prior; Lambda-coalescent; non-parametric inference; posterior consistency; pseudo-marginal MCMC; DNA VARIATION; POPULATION; GENEALOGY; DISTRIBUTIONS; FUNCTIONALS; FINITE; AGE;
D O I
10.3150/16-BEJ923
中图分类号
O21 [概率论与数理统计]; C8 [统计学];
学科分类号
020208 ; 070103 ; 0714 ;
摘要
We investigate Bayesian non-parametric inference of the Lambda-measure of Lambda-coalescent processes with recurrent mutation, parametrised by probability measures on the unit interval. We give verifiable criteria on the prior for posterior consistency when observations form a time series, and prove that any non-trivial prior is inconsistent when all observations are contemporaneous. We then show that the likelihood given a data set of size n is an element of N is constant across Lambda-measures whose leading n - 2 moments agree, and focus on inferring truncated sequences of moments. We provide a large class of functionals which can be extremised using finite computation given a credible region of posterior truncated moment sequences, and a pseudo-marginal Metropolis-Hastings algorithm for sampling the posterior. Finally, we compare the efficiency of the exact and noisy pseudo-marginal algorithms with and without delayed acceptance acceleration using a simulation study.
引用
收藏
页码:2122 / 2153
页数:32
相关论文
共 58 条
[1]   An efficient Monte Carlo method for estimating Ne from temporally spaced samples using a coalescent-based likelihood [J].
Anderson, EC .
GENETICS, 2005, 170 (02) :955-967
[2]   THE PSEUDO-MARGINAL APPROACH FOR EFFICIENT MONTE CARLO COMPUTATIONS [J].
Andrieu, Christophe ;
Roberts, Gareth O. .
ANNALS OF STATISTICS, 2009, 37 (02) :697-725
[3]  
[Anonymous], PREPRINT
[4]  
[Anonymous], PREPRINT
[5]  
[Anonymous], CAMBRIDGE SERIES STA
[6]  
[Anonymous], ELECT J PROBAB
[7]   Mitochondrial cytochrome b DNA variation in the high-fecundity Atlantic cod:: Trans-atlantic clines and shallow gene genealogy [J].
Arnason, E .
GENETICS, 2004, 166 (04) :1871-1885
[8]  
Beaumont MA, 2003, GENETICS, V164, P1139
[9]   THE GENEALOGY OF BRANCHING BROWNIAN MOTION WITH ABSORPTION [J].
Berestycki, Julien ;
Berestycki, Nathanael ;
Schweinsberg, Jason .
ANNALS OF PROBABILITY, 2013, 41 (02) :527-618
[10]   Stochastic flows associated to coalescent processes [J].
Bertoin, J ;
Le Gall, JF .
PROBABILITY THEORY AND RELATED FIELDS, 2003, 126 (02) :261-288