Glucose photoelectrochemical enzyme sensor based on competitive reaction of ascorbic acid

被引：31

作者：

Chen, Delun ^{[1
,2
]}

Wang, Xiaohong ^{[2
]}

Zhang, Kexi ^{[2
]}

Cao, Yang ^{[2
,5
]}

Tu, Jinchun ^{[2
]}

Xiao, Dan ^{[3
,4
]}

Wu, Qiang ^{[1
]}

机构：

[1] Hainan Med Univ, Chinese Acad Med Sci, Minist Educ,Res Unit Isl Emergency Med, Sch Trop Med & Lab Med,Key Lab Emergency & Trauma, 2019RU013, Haikou 571199, Hainan, Peoples R China

[2] Hainan Univ, State Key Lab Marine Resource Utilizat South Chin, Haikou 570228, Hainan, Peoples R China

[3] Sichuan Univ, Key Lab Green & Technol, Minist Educ, Coll Chem, Chengdu 610065, Peoples R China

[4] Sichuan Univ, Coll Chem Engn, Chengdu 610065, Peoples R China

[5] Qiongtai Normal Univ, Haikou 571127, Hainan, Peoples R China

来源：

BIOSENSORS & BIOELECTRONICS | 2020年 / 166卷

基金：

中国国家自然科学基金;

关键词：

ZnO; Competitive reaction; Photoelectrochemical enzyme sensor; OXIDASE; DESIGN;

D O I：

10.1016/j.bios.2020.112466

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

A new method based on the competitive reaction of ascorbic acid (AA) was used to improving the performance of photoelectrochemical glucose enzyme sensor. In this method, amplifying the photoelectric signal of H2O2 by the competitive reaction of AA is the key step. The detection can be well operated at 0 V under optimal AA concentration of 10 mM. In the method, AA was regarded as not only the electron donor to capture the hole in the conduction band of ZnO, but also the remover of H2O2 produced by the oxidation of glucose. Both these factors led to the formation of a pair of competitive reactions that enhanced the response towards glucose detection. Compared to the detection without AA, the stability of the response current, detection ranges of 1-19 mM, detection limit of 80 tiM and sensitivity of 2.88 mu A mM(-1).cm(-2) were optimized prominently.

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页数：5

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