Steroidal Saponins from the Rhizomes of Ruscus hypophyllum

被引：0

作者：

Mimaki, Yoshihiro ^{[1
]}

Aoki, Tsukasa ^{[1
]}

Jitsuno, Maki ^{[1
]}

Yokosuka, Akihito ^{[1
]}

Kilic, Ceyda Sibel ^{[2
]}

Coskun, Maksut

机构：

[1] Tokyo Univ Pharm & Life Sci, Tokyo 1020392, Japan

[2] Ankara Univ, Fac Pharm, TR-06100 Tandogan, Turkey

来源：

NATURAL PRODUCT COMMUNICATIONS | 2008年 / 3卷 / 10期

关键词：

Ruscus hypophyllum; Liliaceae; spirostanol saponins; furostanol saponins; cholestane glycosides; HL-60; cells;

D O I：

暂无

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Phytochemical screening of the rhizomes of Ruscus hypophyllum (Liliaccae) has resulted in the isolation of five spirostanol saponins (1-5) including a new saponin (4) and nine furostanol saponins (6-14) including three new saponins (9-11), together with a known cholestane glycoside (15) and a new cholestane glycoside (16). The structures of the new compounds were determined on the basis of extensive spectroscopic analysis, including 2D NMR data, and chemical evidence. The spirostanol saponins 1, 2, and 5 showed moderate cytotoxic activity against HL-60 human promyelocytic leukemia cells.

引用

页码：1671 / 1678

页数：8

共 13 条

[1] C-13 NMR SPECTRAL INVESTIGATIONS .10. C-13 NMR-SPECTROSCOPY OF STEROIDAL SAPOGENINS AND STEROIDAL SAPONINS [J].