Course of Cognitive Functioning in Institutionalized Persons With Moderate to Severe Dementia: Evidence From the Severe Impairment Battery Short Version

被引:2
|
作者
Wolf, Evelien T. [1 ]
Weeda, Wouter D. [2 ]
Wetzels, Roland B. [3 ,4 ,5 ]
de Jonghe, Jos F. M. [6 ]
Koopmans, Raymond C. T. M. [3 ,4 ,7 ]
机构
[1] Vrije Univ Amsterdam, Sect Clin Neuropsychol, Van Boechorststr 7, NL-1081 BT Amsterdam, Netherlands
[2] Leiden Univ, Dept Psychol, Leiden, Netherlands
[3] Radboud Univ Nijmegen Med Ctr, Dept Primary & Community Care, Nijmegen, Netherlands
[4] Radboud Alzheimer Ctr, Nijmegen, Netherlands
[5] Elderly Care Org, Zzg, Nijmegen, Netherlands
[6] North West Hosp Grp, Geriatr Med, Alkmaar, Netherlands
[7] Ctr Specialized Geriatr Care, Joachim Anna, Nijmegen, Netherlands
关键词
Cognition; Cognitive decline; Dementia; Dementia stages; Institutionalization; Longitudinal studies; Neuropsychological tests; MINI-MENTAL-STATE; ALZHEIMERS-DISEASE; SEMANTIC MEMORY; SHORT-FORM; PREDICTORS; VALIDITY; DONEPEZIL; SERVICES;
D O I
10.1017/S1355617718000991
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Objectives: To adequately monitor the course of cognitive functioning in persons with moderate to severe dementia, relevant cognitive tests for the advanced dementia stages are needed. We examined the ability of a test developed for the advanced dementia stages, the Severe Impairment Battery Short version (SIB-S), to measure cognitive change over time. Second, we examined type of memory impairment measured with the SIB-S in different dementia stages. Methods: Participants were institutionalized persons with moderate to severe dementia (N = 217). The SIB-S was administered at 6-month intervals during a 2-year period. Dementia severity at baseline was classified according to Global Deterioration Scale criteria. We used mixed models to evaluate the course of SIB-S total and domain scores, and whether dementia stage at baseline affected these courses. Results: SIB-S total scores declined significantly over time, and the course of decline differed significantly between dementia stages at baseline. Persons with moderately severe dementia declined faster in mean SIB-S total scores than persons with moderate or severe dementia. Between persons with moderate and moderately severe dementia, there was only a difference in the rate of decline of semantic items, but not episodic and non-semantic items. Conclusions: Although modest floor and slight ceiling effects were noted in severe and milder cases, respectively, the SIB-S proved to be one of few available adequate measures of cognitive change in institutionalized persons with moderate to severe dementia. (JINS, 2019, 25, 204-214)
引用
收藏
页码:204 / 214
页数:11
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