The Impact of Human Mobility on HIV Transmission in Kenya

被引:28
作者
Isdory, Augustino [1 ]
Mureithi, Eunice W. [1 ]
Sumpter, David J. T. [2 ]
机构
[1] Univ Dar Es Salaam, Dept Math, Dar Es Salaam, Tanzania
[2] Uppsala Univ, Dept Math, S-75238 Uppsala, Sweden
关键词
HUMAN-IMMUNODEFICIENCY-VIRUS; EPIDEMIC MODEL; RISK-FACTORS; INFECTION; MIGRATION; SPREAD; HIV/AIDS; DYNAMICS; HETEROGENEITY; ABSTINENCE;
D O I
10.1371/journal.pone.0142805
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Disease spreads as a result of people moving and coming in contact with each other. Thus the mobility patterns of individuals are crucial in understanding disease dynamics. Here we study the impact of human mobility on HIV transmission in different parts of Kenya. We build an SIR metapopulation model that incorporates the different regions within the country. We parameterise the model using census data, HIV data and mobile phone data adopted to track human mobility. We found that movement between different regions appears to have a relatively small overall effect on the total increase in HIV cases in Kenya. However, the most important consequence of movement patterns was transmission of the disease from high infection to low prevalence areas. Mobility slightly increases HIV incidence rates in regions with initially low HIV prevalences and slightly decreases incidences in regions with initially high HIV prevalence. We discuss how regional HIV models could be used in public-health planning. This paper is a first attempt to model spread of HIV using mobile phone data, and we also discuss limitations to the approach.
引用
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页数:21
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