Leishmania (Viannia) spp. dissemination and tissue tropism in naturally infected dogs (Canis familiaris)

被引:15
作者
Reithinger, R
Lambson, BE
Barker, DC
Counihan, H
Espinoza, JC
González, JS
Davies, CR
机构
[1] Univ London London Sch Hyg & Trop Med, Dept Infect & Trop Dis, London WC1E 7HT, England
[2] Univ Cambridge, Dept Pathol, Molteno Inst Parasitol, Cambridge CB2 1QP, England
[3] Direcc Reg Salud Huanuco, Huanuco, Peru
关键词
cutaneous leishmaniasis; Leishmania (Viannia); animal model; dog; PCR; molecular diagnostics; Peru;
D O I
10.1016/S0035-9203(02)90249-X
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
First evidence is presented for Leishmania (Viannia) spp. dissemination and tissue tropism in the domestic dog. Using PCR and histology, parasites were detected in the conjunctiva, lung, lymph nodes and ovaries of 2 naturally infected Peruvian dogs. The detection of parasites in the blood indicates that parasite dissemination to those organs may have been haematogenous.
引用
收藏
页码:76 / 78
页数:3
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