Synaptic-vesicle fusion: a need for speed

被引：3
|
作者：
Munson, Mary [1 ]
机构：
[1] Univ Massachusetts, Sch Med, Dept Biochem & Mol Pharmacol, Worcester, MA 01655 USA
来源：
NATURE STRUCTURAL & MOLECULAR BIOLOGY | 2015年 / 22卷 / 07期
关键词：
NEUROTRANSMITTER RELEASE; TETHERING COMPLEXES; SNARE COMPLEXES; MUNC13; CORVET; HOPS;
D O I：
10.1038/nsmb.3056
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Two new studies reveal mechanistic insights into how neurons control the assembly of SNARE complexes and the rapid fusion of synaptic vesicles. Structural, biophysical and functional experiments are combined to elucidate the roles of two critical regulators: Munc13 and synaptotagmin.
引用
收藏
页码：509 / 511
页数：3
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