Nanomaterials in mass spectrometry ionization and prospects for biological application

被引：67

作者：

Guo, Z ^{[1
]}

Ganawi, AAA ^{[1
]}

Liu, Q ^{[1
]}

He, L ^{[1
]}

机构：

[1] N Carolina State Univ, Dept Chem, Raleigh, NC 27695 USA

来源：

ANALYTICAL AND BIOANALYTICAL CHEMISTRY | 2006年 / 384卷 / 03期

关键词：

nanomaterials; mass spectrometry; bioanalysis;

D O I：

10.1007/s00216-005-0125-3

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The rapid development of nanotechnology has revolutionized scientific developments in recent decades. Mass spectrometry (MS) measurements are no exception and have benefited greatly from integration of nanomaterials in every step of analysis. This brief review summarizes recent developments in the field with the focus on the use of nanomaterials as alternative media to facilitate analyte ionization in laser-desorption ionization-mass spectrometry (LDI-MS) and secondary ion mass spectrometry (SIMS). The biological applications of both techniques are also detailed. The use of nanomaterials in other aspects of MS analysis, for example in sample clean-up and indirect analyte quantification, is briefly discussed.

引用

页码：584 / 592

页数：9

共 67 条

[1] On the mechanism of laser-induced desorption-ionization of organic compounds from etched silicon and carbon surfaces [J].