First trimester vaginal bleeding and adverse pregnancy outcomes among Chinese women: from a large cohort study in China

被引:15
作者
Sun, Lu [1 ]
Tao, Fangbiao [1 ]
Hao, Jiahu [1 ]
Su, Puyu [1 ]
Liu, Fang [1 ]
Xu, Rong [1 ]
机构
[1] Sch Publ Hlth, Dept Maternal Child & Adolescent Hlth, Hefei 230032, Peoples R China
基金
中国国家自然科学基金;
关键词
low birth weight; pregnancy; preterm birth; small for gestational age; vaginal bleeding; PRETERM DELIVERY; RISK; BIRTH;
D O I
10.3109/14767058.2011.632034
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Objectives: To examine the effect of first trimester vaginal bleeding on adverse pregnancy outcomes including preterm delivery, low birth weight and small for gestational age. Methods: This is a prospective population-based cohort study. A questionnaire survey was conducted on 4342 singleton pregnancies by trained doctors. Binary logistic regression was used to estimate risk ratios (RRs) and 95% confidence intervals (95% CI). Results: Vaginal bleeding occurred among 1050 pregnant women, the incidence of vaginal bleeding was 24.2%, 37.4% of whom didn't see a doctor, 62.6% of whom saw a doctor for vaginal bleeding. Binary logistic regression demonstrated that bleeding with seeing a doctor was significantly associated with preterm birth (RR 1.84, 95% CI 1.25-2.69) and bleeding without seeing a doctor was related to increased of low birth weight (RR 2.52, 95% CI 1.34-4.75) and was 1.97-fold increased of small for gestational age (RR 1.97, 95% CI 1.19-3.25). Conclusions: These results suggest that first trimester vaginal bleeding is an increased risk of low birth weight, preterm delivery and small for gestational age. Find ways to reduce the risk of vaginal bleeding and lower vaginal bleeding rate may be helpful to reduce the incidence of preterm birth, low birth weight and small for gestational age.
引用
收藏
页码:1297 / 1301
页数:5
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