The genomic and sequence analysis of rat histone H2B genes

被引：1
|
作者：
Choi, YC
Chae, CB
机构：
[1] Postech, Pohang 790784, South Korea
[2] Jeil Premium 1209, Pohang, South Korea
来源：
DNA SEQUENCE | 1998年 / 9卷 / 5-6期
关键词：
D O I：
10.3109/10425179809008476
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
In addition to previously characterized testis-specific and somatic H2B histone genes, two somatic histone H2B genes, hereafter called sH2B-2 and sH2B-3, were isolated from a rat genomic library, genomic organization was determined, and their promoter was sequenced. Like many other H2B genes, sH2B-2 gene was closely linked to H2A gene whereas H3 gene was located upstream of sH2B-3 gene. Deletion and mutation analysis of 5' sequence fused to CAT reporter gene revealed that the interaction between CCAAT and octamer binding factors is important for S-phase-specific activation of sH2B-3 gene.
引用
收藏
页码：353 / 358
页数：6
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